Abstract: Objective To understand the incidence of pulmonary tuberculosis (TB) and smear-positive TB in residents in Pudong new district of Shanghai. Methods The study subjects were the local residents of Pudong new district during 2008-2014. The standardized morbidity and mortality of TB and smear-positive TB was calculated according to world population data in 1985 and Chinese population data in 1982. The incidence trend of TB and its annual percent changes(APC) from 2008 to 2014 were analyzed by using Join-point regression program. Results A total of 5548 TB cases occurred during 2008-2014, in which 3939 cases were males and 1609 cases were females. The world standardized morbidity was 20.34 per 100 000 population, and China standardized morbidity was 18.92 per 100 000 population. No significantincrease in TB incidence was observed (APC=0.84%, Z=1.68,P=0.15). The age specific incidence peaks were in age group 20-24 years (36.72 per 100 000) and 80-84 years (68.55 per 100 000). A total of 2285 smear-positive TB cases were reported, The world standardized morbidity was 7.32 per 100 000 population, and the China standardized morbidity was 6.45 per 100 000 population. The incidence showeda significant decline (APC=-4.22%, Z=3.41,P=0.01), which was more obvious in males (APC=-4.51%, Z=6.77, P 0.01) than in females (APC=-2.20% Z=1.16, P=0.29). Conclusion It is necessary to pay more attention to TB susceptible population and take effective measures to identify risk factors forgetting TB for the reduction of TB incidence.