艾尔肯·吾布力, 阿衣夏木·克尤木, 王海燕, 陈鹏高, 热甫开提·阿布力米提, 木合塔尔·艾山. 新疆察布查尔锡伯自治县布鲁氏菌病治疗效果及影响因素分析[J]. 疾病监测, 2018, 33(11): 967-970. DOI: 10.3784/j.issn.1003-9961.2018.11.020
引用本文: 艾尔肯·吾布力, 阿衣夏木·克尤木, 王海燕, 陈鹏高, 热甫开提·阿布力米提, 木合塔尔·艾山. 新疆察布查尔锡伯自治县布鲁氏菌病治疗效果及影响因素分析[J]. 疾病监测, 2018, 33(11): 967-970. DOI: 10.3784/j.issn.1003-9961.2018.11.020
Arkin·obol, Ayxam·kiyom, Wang Haiyan, Chen Penggao, Ripkat·abulimit, Muhtar·hasan. InvestigationofbrucellosistreatmenteffectandinfluencingfactorsinQapqalXibeautonomouscountyofXinjiang[J]. Disease Surveillance, 2018, 33(11): 967-970. DOI: 10.3784/j.issn.1003-9961.2018.11.020
Citation: Arkin·obol, Ayxam·kiyom, Wang Haiyan, Chen Penggao, Ripkat·abulimit, Muhtar·hasan. InvestigationofbrucellosistreatmenteffectandinfluencingfactorsinQapqalXibeautonomouscountyofXinjiang[J]. Disease Surveillance, 2018, 33(11): 967-970. DOI: 10.3784/j.issn.1003-9961.2018.11.020

新疆察布查尔锡伯自治县布鲁氏菌病治疗效果及影响因素分析

InvestigationofbrucellosistreatmenteffectandinfluencingfactorsinQapqalXibeautonomouscountyofXinjiang

  • 摘要:
      目的  为调查察布查尔锡伯自治县布鲁氏菌病(布病)治疗现况、评估治疗效果和分析治疗效果的影响因素,为进一步做好布病综合防治工作提供参考依据。
      方法  通过查阅布病病例管理调查表、临床病案以及入户面访等方式收集资料,按照布病诊疗指南进行临床类型和疗效判定。
      结果  急性期治愈率(74.48%)明显高于慢性期(23.81%),二者差异有统计学意义(χ2=22.92,P=0.01),logistic回归多因素分析结果显示,发病与诊疗间隔(OR=11.62, 95%CI:2.11 ~ 64.32,OR=7.54, 95%CI:1.82 ~ 30.94)、治疗期间停药(OR=11.81, 95%CI:3.82 ~ 36.35)、疗程不足6周(OR=4.34, 95%CI:1.62 ~ 11.56)、私人诊所治疗(OR=10.39,95%CI:1.72 ~ 62.03)、治疗期间继续接触牲畜(OR=3.82, 95%CI:1.42 ~ 8.17)和饮用生奶(OR=26.15, 95%CI:1.93 ~ 344.07)是影响治疗效果的潜在因素。
      结论  察布查尔锡伯自治县布病治疗效果不理想。今后布病诊疗工作的重点是基层医疗人员对居家治疗的患者要定期跟踪随访、观察患者治疗效果、督导其按疗程规范服药、要强化患者的自我管理、提高治愈率。

     

    Abstract:
      Objective  To investigate the current status of treatment of brucellosis in Qapqal Xibo autonomous county of Xinjiang, evaluate treatment effect and analyze the related factors, and provide reference for further comprehensive prevention and control of brucellosis.
      Methods  The data were collected through the reviews of the survey results and clinical records as well as household interviews. The same criteria were used to classify the clinical type of brucellosis and evaluate the treatment effect.
      Results  The cure rate of brucellosis in acute phase (74.48%) was significantly higher than that of brucellosis in chronic phase (23.81%), the difference was significant (χ2=22.92, P=0.01), The multivariate logistic regression analysis showed that the interval between onset and diagnosis(OR=11.62, 95% CI: 2.11−64.32, OR=7.54, 95% CI: 1.82−30.94, drug withdrawal (OR=11.81, 95% CI: 3.82−36.35), treatment less than 6 weeks (OR=4.34, 95% CI: 1.62−11.56), treatment in private clinic (OR=10.39, 95% CI: 1.72−62.03), contacting livestock during treatment (OR=3.82, 95% CI: 1.42−8.17), drinking raw milk during treatment (OR=26.15, 95% CI: 1.93−344.07) were the potential factors influencing the treatment effect.
      Conclusion  The treatment effect of brucellosis in Qapqal Xibe autonomous county is not satisfied. In the future, the priority of brucellosis diagnosis and treatment should be the regular follow up for non-hospitalized patients by primary health care providers to observe the treatment effect and supervise their medication according to the prescription and strengthen the patient's self-management for the increase of the cure rate of brucellosis.

     

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