张玉, 侯双翼, 周丽平, 张梦娴, 卢星星, 皮琦, 杨成凤. 2007-2017年湖北省利福平耐药肺结核流行病学特征分析[J]. 疾病监测, 2019, 34(7): 667-671. DOI: 10.3784/j.issn.1003-9961.2019.07.019
引用本文: 张玉, 侯双翼, 周丽平, 张梦娴, 卢星星, 皮琦, 杨成凤. 2007-2017年湖北省利福平耐药肺结核流行病学特征分析[J]. 疾病监测, 2019, 34(7): 667-671. DOI: 10.3784/j.issn.1003-9961.2019.07.019
Yu Zhang, Shuangyi Hou, Liping Zhou, Mengxian Zhang, Xingxing Lu, Qi Pi, Chengfeng Yang. Epidemical characteristics of rifampicin-resistant tuberculosis in Hubei, 2007–2017[J]. Disease Surveillance, 2019, 34(7): 667-671. DOI: 10.3784/j.issn.1003-9961.2019.07.019
Citation: Yu Zhang, Shuangyi Hou, Liping Zhou, Mengxian Zhang, Xingxing Lu, Qi Pi, Chengfeng Yang. Epidemical characteristics of rifampicin-resistant tuberculosis in Hubei, 2007–2017[J]. Disease Surveillance, 2019, 34(7): 667-671. DOI: 10.3784/j.issn.1003-9961.2019.07.019

2007-2017年湖北省利福平耐药肺结核流行病学特征分析

Epidemical characteristics of rifampicin-resistant tuberculosis in Hubei, 2007–2017

  • 摘要:
    目的分析利福平耐药肺结核(RR-TB)患者的流行病学特征,为耐药结核病控制工作提供参考信息。
    方法利用描述性研究和基于地理信息系统的可视化展示技术,对2007 — 2017年湖北省RR-TB患者数据进行回顾性分析。
    结果2007 —2017年湖北省共登记RR-TB患者3 012例,其中耐多药结核病2 669例,占88.61%。 两者的年均登记率分别为0.47/10万和0.42/10万,登记率均呈上升趋势(趋势χ2=763.033、506.672,均P<0.001)。 RR-TB患者中男性(75.60%)多于女性(24.40%),以中青年人群为主,>45岁组患者所占比例最高(23.97%)。 2007 — 2017年湖北省不同地市RR-TB登记率范围为0.03/10万 ~ 1.26/10万,复治患者RR-TB检出率(28.84%)高于初治患者(7.05%)。
    结论2007 — 2017年湖北省RR-TB登记呈逐年上升趋势,以中青年患者为主,男性、复治患者所占比例较大,提示应加强结核病防治规划工作,注重RR-TB筛查、治疗和管理,减少耐药结核病的传播。

     

    Abstract:
    ObjectiveTo understand the epidemiological characteristics of rifampicin-resistant tuberculosis (RR-TB) in Hubei province from 2007 to 2017, and provide scientific evidence for drug-resistant TB prevention and control.
    MethodsA retrospective analysis on the prevalence of RR-TB in Hubei was conducted using descriptive epidemiological method and GIS visualization technique.
    ResultsFrom 2007 to 2017, a total of 3 012 RR-TB cases were registered in Hubei, including 2 669 cases of multidrug-resistant TB (MDR-TB), accounting for 88.61%. The annual registration rates of RR-TB and MDR-TB were 0.47/100 000 and 0.42/100 000 respectively, and the registration rates showed an upward trend (trends χ2 =763.033, 506.672, P<0.001). Among RR-TB cases, males accounted for 75.60%, females accounted for 24.40%. The cases were mainly young and middle-aged adults, those aged >45 years accounted for 23.97%. From 2007 to 2017, the RR-TB registration rates in different areas ranged from 0.03/100 000 to 1.26/100 000. The detection rate of RR-TB in the retreated cases was 28.84%, higher than that in the newly diagnosed cases (7.05%).
    ConclusionThe registration rate of RR-TB increased with year in Hubei from 2007 to 2017, the cases were mainly young and middle-aged adults. Male cases and retreated cases accounted for higher proportions. It is suggested to strengthen the prevention and treatment of TB, as well as the screening, treatment and management of RR-TB to reduce the spread of drug-resistant TB.

     

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