糜跃萍, 胡迪, 蔡波, 徐红, 俞浩. 1990-2019年江苏省胰腺癌疾病负担和危险因素分析[J]. 疾病监测, 2022, 37(10): 1376-1382. DOI: 10.3784/jbjc.202202220054
引用本文: 糜跃萍, 胡迪, 蔡波, 徐红, 俞浩. 1990-2019年江苏省胰腺癌疾病负担和危险因素分析[J]. 疾病监测, 2022, 37(10): 1376-1382. DOI: 10.3784/jbjc.202202220054
Mi Yueping, Hu Di, Cai Bo, Xu Hong, Yu Hao. Disease burden and related risk factors of pancreatic cancer in Jiangsu, 1990−2019[J]. Disease Surveillance, 2022, 37(10): 1376-1382. DOI: 10.3784/jbjc.202202220054
Citation: Mi Yueping, Hu Di, Cai Bo, Xu Hong, Yu Hao. Disease burden and related risk factors of pancreatic cancer in Jiangsu, 1990−2019[J]. Disease Surveillance, 2022, 37(10): 1376-1382. DOI: 10.3784/jbjc.202202220054

1990-2019年江苏省胰腺癌疾病负担和危险因素分析

Disease burden and related risk factors of pancreatic cancer in Jiangsu, 1990−2019

  • 摘要:
      目的  分析1990—2019年江苏省居民胰腺癌流行情况、疾病负担变化趋势和相关危险因素,为胰腺癌防治提供依据。
      方法  利用2019年全球疾病负担研究(GBD2019)数据,分别计算发病率、患病率、死亡率和伤残调整寿命年(DALYs)率等指标;采用Joinpoint软件计算胰腺癌标化发病率、患病率、死亡率和DALYs率的年度变化百分比(APC)和平均年度变化百分比(AAPC);分析归因于烟草使用、高空腹血糖值(FPG)和高体质指数(BMI)对胰腺癌疾病负担变化的影响。
      结果  1990—2019年江苏省居民胰腺癌标化发病率、标化患病率、标化死亡率和标化DALYs率整体呈上升趋势(AAPC分别为2.0%、2.2%、1.9%和1.7%)。 疾病负担中标化DALYs率由1990年的118.24/10万上升至2019年的196.39/10万,增幅为66.09%,其中男性增幅大于女性。 与1990年相比,2019年归因于烟草使用、高FPG和高BMI的标化死亡率和标化DALYs率均上升。 65岁及以上人群疾病负担上升明显,且男性疾病负担高于女性。
      结论  1990—2019年江苏省居民胰腺癌疾病负担仍较重。 对于有吸烟史、血糖值异常和高BMI的老年男性群体应做重点防治和健康宣教,加强控烟并倡导健康饮食,降低胰腺癌死亡人数和疾病负担。

     

    Abstract:
      Objective  To analyze the prevalence and the trend of disease burden of pancreatic cancer and related risk factors in Jiangsu province during 1990−2019 and provide evidence for the prevention and treatment of pancreatic cancer.
      Methods  The data of 2019 Global Burden of Disease Study (GBD2019) were used to calculate the incidence rate, prevalence rate, mortality rate and disability adjusted life years (DALYs) rate of pancreatic cancer. Software Joinpoint was used to calculate the annual percent change (APC) and average annual percent change (AAPC) of the incidence rate, prevalence rate, mortality rate and DALYs rate. The effects of smoking, high fasting plasma glucose (FPG) and high body-mass index (BMI) on the burden of pancreatic cancer were also analyzed.
      Results  The standardized incidence rate, prevalence rate, mortality rate and DALYs rate of pancreatic cancer increased in Jiangsu from 1990 to 2019 (AAPC=2.0%, 2.2%, 1.9%, 1.7%). The standardized DALYs rate increased by 66.09% from 118.24/100 000 in 1990 to 196.39/100 000 in 2019, the growth rate was higher in men than in women. Compared with 1990, the standardized mortality rate and standardized DALYs rate due to smoking, high FPG and high BMI increased in 2019. The disease burden in people over 65 years old increased significantly, and the disease burden was higher in men than in women.
      Conclusion  In recent 30 years, the disease burden of pancreatic cancer was still heavy in Jiangsu. It is necessary to improve the prevention and control of pancreatic cancer in elderly men, especially in those with smoking history, abnormal blood sugar value and high BMI, and strengthen smoking control and promote healthy diet to reduce the death and disease burden of pancreatic cancer.

     

/

返回文章
返回