陈纯, 谢华萍, 汪慧, 耿进妹, 鲁影, 王大虎, 李美霞, 李铁钢. 2013-2017年广东省广州市肠道病毒71型感染所致手足口病病例的流行特征分析[J]. 疾病监测, 2019, 34(8): 737-740. DOI: 10.3784/j.issn.1003-9961.2019.08.013
引用本文: 陈纯, 谢华萍, 汪慧, 耿进妹, 鲁影, 王大虎, 李美霞, 李铁钢. 2013-2017年广东省广州市肠道病毒71型感染所致手足口病病例的流行特征分析[J]. 疾病监测, 2019, 34(8): 737-740. DOI: 10.3784/j.issn.1003-9961.2019.08.013
Chun Chen, Huaping Xie, Hui Wang, Jinmei Geng, Ying Lu, Dahu Wang, Meixia Li, Tiegang Li. Epidemiological characteristics of hand foot and mouth disease cases caused by enterovirus 71 in Guangzhou, 2013–2017[J]. Disease Surveillance, 2019, 34(8): 737-740. DOI: 10.3784/j.issn.1003-9961.2019.08.013
Citation: Chun Chen, Huaping Xie, Hui Wang, Jinmei Geng, Ying Lu, Dahu Wang, Meixia Li, Tiegang Li. Epidemiological characteristics of hand foot and mouth disease cases caused by enterovirus 71 in Guangzhou, 2013–2017[J]. Disease Surveillance, 2019, 34(8): 737-740. DOI: 10.3784/j.issn.1003-9961.2019.08.013

2013-2017年广东省广州市肠道病毒71型感染所致手足口病病例的流行特征分析

Epidemiological characteristics of hand foot and mouth disease cases caused by enterovirus 71 in Guangzhou, 2013–2017

  • 摘要:
    目的分析广东省广州市肠道病毒71型(EV71)所致手足口病病例的流行特征。
    方法通过整理2013 — 2017年广州市5家监测点医院EV71手足口病的感染情况,结合大疫情网中手足口病重症病例、死亡病例和暴发疫情数据,定义估算公式。 采用χ2检验进行数据分析。
    结果2013 — 2017年广州市手足口病重症病例和死亡病例中EV71阳性分别占53.85%和100.00%,哨点监测手足口病普通病例中EV71阳性率为12.21%。 估算EV71感染所致手足口病2014年发病率最高,为134.36/10万。 高发月份主要集中在每年的4 — 6月;发病人群以≤5岁,特别是1 ~ 3岁的儿童为主,但重症病例和死亡病例多发于0 ~ 1岁婴幼儿。
    结论2013 — 2017年EV71是导致广州市手足口病重症死亡病例的重要病原体,医疗机构应重点做好EV71所致手足口病病例,特别是1 ~ 3岁病例的重症早期识别与救治,减少危重病例,降低病死率。

     

    Abstract:
    ObjectiveTo understand the epidemiological characteristics of hand foot and mouth disease (HFMD) cases caused by enterovirus 71 (EV71) in Guangzhou from 2013 to 2017.
    MethodsThe incidence data of HFMD cases caused by EV71 were collected from 5 sentinel hospitals in Guangzhou, including severe and fatal cases and outbreaks of HFMD, the estimation formula was defined, and χ2 test was used for the data comparison.
    ResultsFrom 2013 to 2017, severe cases and fatal cases in Guangzhou accounted for 53.85% and 100.00%, respectively, in EV71 caused HFMD cases. The positive rate of EV71 in mild HFMD cases from sentinel hospitals was 12.21%. The highest estimated incidence rate of EV71 infection was in 2014 (134.36/100 000). The annual incidence peak was during April-June. The incidence was higher in age group below 5 years old, especially in children aged 1–3 years. However, severe and fatal cases mostly occurred in infants aged 0–1 year.
    ConclusionIn Guangzhou, EV71 was the most important pathogen causing severe and fatal cases of HFMD. Medical institutions should focus on the early identification and treatment of EV71 caused severe cases of HFMD, especially in children aged 1–3 years.

     

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