Objective  To analyze the epidemiological characteristics of mumps in Fengxian district of Shanghai from 2005 to 2019, and provide evidence for mumps prevention and control.

  Methods  The incidence data of mumps in Fengxian from 2005 to 2019 were collected from national information system of disease prevention and control for a descriptive analysis.

  Results  A total of 2900 mumps cases were reported in Fengxian from 2005 to 2019, the average annual incidence rate was 19.31/100 000. The annual case number ranged from 89 (2018) to 438 (2007), and annual incidence rates ranged from 8.26/100 000 (2018) to 54.78/100 000 (2009). The incidence was higher in males than in females. Most cases occurred in age group 5–9 years. The annual incidence peak occurred during April-July. More cases occurred in local population than in floating population, and more cases occurred in people without mumps containing vaccine (MuCV) immunization history or with unknown MuCV immunization history than in those with MuCV immunization history.

  Conclusion  The overall incidence of mumps decreased in Fengxian from 2005 to 2019, but the incidence in children aged 5–9 years was still high. It is suggested to strengthen mumps surveillance and promote routine immunization in children for the prevention and control of mumps outbreak.