吴健, 张佳玉, 王旭婷, 舒伟萍, 徐元, 秦晓云, 宁镇. 2012-2019年上海市男男性行为哨点人群HIV-1感染情况及影响因素分析[J]. 疾病监测, 2021, 36(5): 452-456. DOI: 10.3784/jbjc.202110300371
引用本文: 吴健, 张佳玉, 王旭婷, 舒伟萍, 徐元, 秦晓云, 宁镇. 2012-2019年上海市男男性行为哨点人群HIV-1感染情况及影响因素分析[J]. 疾病监测, 2021, 36(5): 452-456. DOI: 10.3784/jbjc.202110300371
Wu Jian, Zhang Jiayu, Wang Xuting, Shu Weiping, Xu Yuan, Qin Xiaoyun, Ning Zhen. HIV-1 infection and influencing factors in MSM in sentinel surveillance, Shanghai, 2012–2019[J]. Disease Surveillance, 2021, 36(5): 452-456. DOI: 10.3784/jbjc.202110300371
Citation: Wu Jian, Zhang Jiayu, Wang Xuting, Shu Weiping, Xu Yuan, Qin Xiaoyun, Ning Zhen. HIV-1 infection and influencing factors in MSM in sentinel surveillance, Shanghai, 2012–2019[J]. Disease Surveillance, 2021, 36(5): 452-456. DOI: 10.3784/jbjc.202110300371

2012-2019年上海市男男性行为哨点人群HIV-1感染情况及影响因素分析

HIV-1 infection and influencing factors in MSM in sentinel surveillance, Shanghai, 2012–2019

  • 摘要:
      目的  了解2012 — 2019年上海市男男性行为人群(MSM)的人类免疫缺陷病毒-1(HIV-1)感染和相关行为情况,探索MSM HIV感染的影响因素,为制定MSM的艾滋病防治措施提供依据。
      方法  2012 — 2019年对上海市MSM开展哨点监测,采集研究对象静脉血进行HIV、HCV及梅毒抗体检测,用logistic回归模型分析MSM HIV感染的影响因素。
      结果  2012 — 2019年共检测MSM 3 207人,以25~34岁、未婚、非本市户籍、本地居住时间超过2年、大专及以上文化程度为主,预防艾滋病服务措施覆盖率中位数86.3%,艾滋病相关知识知晓率中位数94.6%。 HIV抗体阳性检出率中位数为6.5%,总体呈上升趋势(P<0.001)。 85.2%调查对象最近 6 个月与同性发生过肛交性行为,其中坚持使用安全套的比例为 79.3%。 最近6个月与同性肛交性行为、商业性行为或异性性行为时使用安全套均呈上升趋势(P<0.05)。 多因素分析显示,文化程度高中及以下(OR=1.506,95%CI:1.067~2.126,P=0.020)、每次同性肛交性行为都未使用安全套(OR=1.379,95%CI:1.005~1.891,P=0.047)、吸毒(OR=3.688,95%CI:1.412~9.634,P=0.008)及感染梅毒(OR=5.872,95%CI:3.784~9.111,P<0.001)为HIV感染的危险因素。
      结论  上海市MSM HIV抗体阳性率持续保持较高水平,艾滋病相关危险行为仍然存在,须进一步探索针对性的有效干预模式,减少艾滋病相关危险行为发生和传播。

     

    Abstract:
      Objective  To investigate the infection status of human immunodeficiency virus-1 (HIV-1) and related behaviors in men who have sex with men (MSM) in Shanghai, identify the influencing factors, and provide evidence for HIV prevention and control.
      Methods  Consecutive sentinel surveillance in MSM were conducted from 2012 to 2019. Blood samples were collected from the MSM and tested for HIV, syphilis and hepatitis C virus (HCV) antibodies. Logistics regression analysis was used to identify the influencing factors.
      Results  A total of 3207 MSM were investigated from 2012 to 2019, they were mainly aged 25–34 years, unmarried and non-local population, and lived in Shanghai for more than 2 years. Most of them had college education or above. The median of coverage rate of AIDS prevention service was 86.3%, and the median of awareness rate of AIDS related knowledge was 94.6%. The median of HIV antibody positive rate was 6.5%, which showed an overall upward trend (P<0.001). Up to 85.2% of MSM reported that they had anal homosexual behaviors in the past six months, among these MSM, 79.3% used condom at each anal sex. In the past six months, the proportions of condom use in homosexual, commercial homosexual and heterosexual behaviors all increased (P<0.05). Multivariate logistic regression analysis showed, education level of senior high school or lower (OR=1.506, 95% CI: 1.067–2.126, P=0.020), non-consistent condom use in anal sex (OR=1.379, 95% CI: 1.005–1.891, P=0.047), drug use (OR=3.688, 95% CI: 1.412–9.634, P=0.008) and syphilis status (OR=5.872, 95% CI: 3.784–9.111, P<0.001) were risk factors for HIV infection.
      Conclusion  The positive rate of HIV antibody in MSM in Shanghai is still high, and HIV related risk behaviors are still common. It is necessary to further explore a comprehensive prevention and control intervention model to reduce the HIV infection in MSM.

     

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