赵玉良, 田茶, 卜桂珍, 刘彩云, 张双宅, 付秀湘, 李书彬, 陈淑芬, 康铁军, 孙永德. 河北省供血员农村居民血清谷丙转氨酶异常的流行因素分析[J]. 疾病监测, 1995, 10(9): 261-265. DOI: 10.3784/j.issn.1003-9961.1995.9.261
引用本文: 赵玉良, 田茶, 卜桂珍, 刘彩云, 张双宅, 付秀湘, 李书彬, 陈淑芬, 康铁军, 孙永德. 河北省供血员农村居民血清谷丙转氨酶异常的流行因素分析[J]. 疾病监测, 1995, 10(9): 261-265. DOI: 10.3784/j.issn.1003-9961.1995.9.261
Zhao Yuliang. et al, . Study on the Risk Factors of Abnormal Alanine Aminotransferase of blood donors (ALT ) in three villages of Hebei province[J]. Disease Surveillance, 1995, 10(9): 261-265. DOI: 10.3784/j.issn.1003-9961.1995.9.261
Citation: Zhao Yuliang. et al, . Study on the Risk Factors of Abnormal Alanine Aminotransferase of blood donors (ALT ) in three villages of Hebei province[J]. Disease Surveillance, 1995, 10(9): 261-265. DOI: 10.3784/j.issn.1003-9961.1995.9.261

河北省供血员农村居民血清谷丙转氨酶异常的流行因素分析

Study on the Risk Factors of Abnormal Alanine Aminotransferase of blood donors (ALT ) in three villages of Hebei province

  • 摘要: 对供血员较多的三个村2505位居民血清ALT异常与各型肝炎病毒感染标志的关系进行了一半动态观察。首次检测ALT异常率为3.27%(82/2505),抗-HCV阳性和饮酒是ALT异常的主要危险因素且二者有联合作用。一年后ALT异常率为3.22%(67/2079);原ALT异常者24.64%(17/69)仍异常,与ALT持续异常有关的主要因素是抗-HCV,阳性者持续率为44.44%(4/9),阴性者持续率为11.63%(5/43);原ALT正常者中有50人(2.49%)发生异常,抗-HCV阳性和饮酒是发生ALT异常的危险因素。甲型和乙型肝炎病毒感染对ALT异常率及正常者一年后异常发生率的影响就总体人群而言均无统计学意义,但对儿童可能起主要作用。

     

    Abstract: An one year dynamic observation on the risk factors of Alanine Aminotransferase (ALT) eleva- tion was carried out in 2505 blood donor from 3 villages of Hebei province. The ALT abnormal rate was 3. 27% (82/2505) when tested in the first time. Anti-HCV positive and alcohol abusing were the main risk factors for the ALT abnormal conversion. A year later, 24.64% (17/69) of the ALT abnor- mal persons remained still abnormal , 2. 49% (50/2505) of the normal ALT persons converted to ab- normal, the ALT abnormal rate became to 3.22%(67/2079).Anti-HCV was the only factor which significantly affected the ALT persistent positive rate.For the anti-HCV positive persons,the ALT per-sistent positive rate was 44.4%(4/9).And for the negative ones,it was 11.63%(5/43),which was significantly lower than the former.The infections of Hepatitis Type B Virus(HBV) and Hepatitis Type A Virus(HAV) were showed no significant influence on the abnormal rate and one-year abnor-mal conversion rate of ALT in the whole population,but seemed play main role in children.

     

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