浙江省 1988～1995 年伤寒沙门氏菌病原学监测研究

Etiological Surveillance of Salmonella Typhi in Zhejiang Province 1988～1995

摘要: 本文报告了浙江省１９８８～１９９５年收集的１３５１株伤寒沙门氏菌的噬菌体分型和耐药性测定结果。共分出２４个噬菌体型别，以Ｍ１、Ａ、Ｄ２、Ｅ１等型为主，分型率为８３．１２％。耐药性测定结果表明，伤寒沙门氏菌对氟哌酸和丁胺卡那霉素的敏感率在９９％以上。伤寒菌对抗菌药物的耐药性主要与流行菌株的噬菌体型别有关，Ｍ１型与非Ｍ１型菌株的耐药性有显著差异。

Abstract: This paper reports the results of phage typing and antibiotic resistance of 1351 strains of Salmonella Typhi collected in Zhejiang Province in 1988～1995.The organisms were divided into 24 types by Vi bacteriophages.The total typing rate was 83.12%.M1,A,D2 and E1 were the main types. It was found that more than 99% strains were sensitive to NOR and AKN.The resistance of Salmonella typhi was related to phage typing of epidemic strains.The resistance of M1 was significantly higher than that of non M1.