Abstract: The data indicated that the major sources of infection of HFRS were Apodemus agrarius in field;Rattus norvegicus and R.flavipectus in door in Hubei Province.The average densities,virus carrier rate and infectious rate of rodents in fall and winter were less than that in spring.There was significant difference of human latent infectious rates among various geographical areas.The human latent infectious rate in south west mountain area was more higher than that in the others.The season contribution of HFRS was double peak pat-tern in whole province.The infectious focux was mixed type with the main type of Apodemus agrarius. The case number of fall witer peak was decreased when compared with the past years. This was one of the factors which made the epidemic status more stable.