陈志军, 刘彩云, 王和平, 孙德贵, 贾文龙, 刘洪海, 刘景龙, 于爱林, 王佑春, 张华远. 输血后庚型肝炎的前瞻性研究[J]. 疾病监测, 2000, 15(1): 8-12. DOI: 10.3784/j.issn.1003-9961.2000.1.8
引用本文: 陈志军, 刘彩云, 王和平, 孙德贵, 贾文龙, 刘洪海, 刘景龙, 于爱林, 王佑春, 张华远. 输血后庚型肝炎的前瞻性研究[J]. 疾病监测, 2000, 15(1): 8-12. DOI: 10.3784/j.issn.1003-9961.2000.1.8
Chen Zhijun. et al, . A Prospective Study on Post-transfusion Hepatits G[J]. Disease Surveillance, 2000, 15(1): 8-12. DOI: 10.3784/j.issn.1003-9961.2000.1.8
Citation: Chen Zhijun. et al, . A Prospective Study on Post-transfusion Hepatits G[J]. Disease Surveillance, 2000, 15(1): 8-12. DOI: 10.3784/j.issn.1003-9961.2000.1.8

输血后庚型肝炎的前瞻性研究

A Prospective Study on Post-transfusion Hepatits G

  • 摘要: 为探讨输血后庚型肝炎的发病率,1997 年2 月开始,我们采用前瞻性研究方法,对102名住院输血病人进行了12 个月的随访研究。113 名献血员提供的113 份血液中单纯ALT 异常率3.5 % (4/113) ,抗- HGV阳性率8.9 % (10/113) ,抗- HCV 阳性率3.5 % (4/113) ;输血后HGV 感染率为3.8 % (4/102) ;10 人输入抗- HGV 阳性血,输血后HGV 感染4 例,其中PT- HG2 例,PT- HG潜伏期38 ~62 天,平均45 天;抗- HGV 最早检出时间为输血后38 天,最迟为96 天,平均为63.5 天;PT- HC发病率为4.9% (5/102) ,5 例PT- HC 中4 例输入抗- HCV 阳性血,1 例输入单纯ALT异常血,PT- HCV 感染率为100 % ,证实HGV 可经血传播,HG 的慢性化程度较高,HGV可形成慢性携带;抗- HCV 阳性血具有很强的传染性。

     

    Abstract: To investigate the morbidity rate of post-transfusion Hepatitis G,we followed up 102 transfused patients in hospital for 12 months with a prospective study method from Feb,1997.In all of 113 blood samples provided by 113 blood donors, abnormal simple ALT rate was 3.5%(4/113). Anti-HGV positive rate was 8.9%(10/113). Anti-HCV positive rate was 3.5%(4/113).Ten of 102 patients were transfused by anti-HGV positive blood, 4 of them were infected with HGV and 2 patients were PT-HG.The infection rate of HGV after transfusion was 3.8%(4/102).The incubation time of PT-HG was 38-62 days,average 45 days.Anti-HGV could be detected since 38 days to 96 days after transfussion,average 63.5 days.The incidence rate of PT-HC was 4.9%(5/102).Of 5 patients 4 were transfused by anti-HC positive blood and 1 was transfused by simple ALT abnormal blood.It was proved that HGV could be transmitted by transfusion and formed a chronic virus carrier.

     

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