肾综合征出血热人间疫情与宿主动物监测分析

Surveillance of Human HFRS and Animals Infecton in Zhejiang Province

摘要: 目的　为掌握肾综合征出血热 (HFRS)流行特征 ,以制定有针对性的防治措施。方法　采用间接免疫荧光法 (IFAT)检测EHF病人血清中抗体 ,采用直接免疫荧光法 (FAT)检测鼠肺汉坦病毒 (HV)抗原。结果　全省 1973例病人 ,主要分布在衢州、绍兴、台州、宁波等市 ,夏季和冬春季有二个发病高峰 ,青壮年农民发病最多。结论　对以姬鼠型为主的混合型疫区 ,应选择双价疫苗进行预防接种 ,以控制发病.

Abstract: Objective To study the epidemic characteristics and make the preventive strategy of HFRS. Methods FAT was used to detected HV antigen in lungs of mouse, and IFAT for antibody detection in HFRS patients. Results All 1973 cases of the whole province were mainly distributed in Shaoxing, Quzhou, Ningbo,Taizhou, Lishui and Jinhua of Zhejiang province. Summer and winter were the two peak periods of HFRS in Zhejiang. Most of the cases were young strong peasants. Conclusion Apodemus agrarius was the main mouse in mixed type areas,we should select bivalent vaccine for decrease the incidence of HFRS.