Abstract:
Objective To Learn the relationship between immunity function of HIV infectors/AIDS patients
and the courses of disease in yunnan province; and to explore the lab specifications of
HIV/AIDS treatment suitable to the situation of yunnan province. Methods To collect 325
cases of HIV/AIDS out - patient data in epidemiology; to use a venous blood application flow
cell counter to the absolute counting for CD4 and CDg with the Trucount fluorescent mark
single - clone ami - body reagent box; and to mensurate the number of carried virus on the
151 cases with the b-DNA/RNA 3.3 A ssay edition.Results (1)The CD4/CD8
of 165 cases of HIV infectors and 160 cases of AIDS patients all had no sexual difference
(P>0.05).(2) The CD4,CD8and CD4/CD8of HIV
infectors and AIDS patients all had no age diffence (P>0.05).(3)The
CD4,CD8and CD4/CD8of HIV infectors and AIDS
patients all had no difference (P>0.05)between Han and Dai nationality.(4)The CD4
cell numbers were less than the number of a normal contrast group.There were significant
difference among three numbers (P4 cell number of group A
was>350/μl;the CD4 cell number of group B was 350-200/μl;the CD4
cell number of group Cwas 4/CD8 and the
virus carried number among the three groups all had considerable difference (P4 and CD4/CD8,the virus carried number
went up increasingly showing the negative relation-ship(r=-0.369,P8
number of group A and group B had no considerable difference (P>0.05),and they both had
obvious difference from group C (P4 and CD8 and
CD4/CD8 of AIDS patients had a relationship with the spectrum of
disease.Conclusion The CD4,CD8 and CD4/CD8of HIV
ivfectiors and AIDS patients had no difference in age,sex and nationality. However,the
CD4 and CD4/CD8 would drop considerably with the added
exposure time.The virus carried number and clinical procedure of CD4 and
CD8 and CD4/CD8 were obviously relevant. The CD4
and CD4/CD8 had a negative relationship with the virus carried
number.The CD4 and virus carried number could be used as important index to
approve the development of disease and the curative effect of medicine.For the present
curative guideline,the CD4/CD8 of AIDS patients had a relationship
with the spectrum of disease.They could be used as the important index to prevent
opportunity infection and instruct using themedicine.