方春福, 余樟友, 王炜. 2002~2004年衢州市肾综合征出血热监测分析[J]. 疾病监测, 2005, 20(10): 513-517. DOI: 10.3784/j.issn.1003-9961.2005.10.513
引用本文: 方春福, 余樟友, 王炜. 2002~2004年衢州市肾综合征出血热监测分析[J]. 疾病监测, 2005, 20(10): 513-517. DOI: 10.3784/j.issn.1003-9961.2005.10.513
FANG Chun-fu, YU Zhang-you, WANG Wei. Surveillance and Analysis of Hemorrhagic Fever with Renal Syndrome (HFRS) from 2002 to 2004 in Quzhou City[J]. Disease Surveillance, 2005, 20(10): 513-517. DOI: 10.3784/j.issn.1003-9961.2005.10.513
Citation: FANG Chun-fu, YU Zhang-you, WANG Wei. Surveillance and Analysis of Hemorrhagic Fever with Renal Syndrome (HFRS) from 2002 to 2004 in Quzhou City[J]. Disease Surveillance, 2005, 20(10): 513-517. DOI: 10.3784/j.issn.1003-9961.2005.10.513

2002~2004年衢州市肾综合征出血热监测分析

Surveillance and Analysis of Hemorrhagic Fever with Renal Syndrome (HFRS) from 2002 to 2004 in Quzhou City

  • 摘要: 目的掌握肾综合征出血热(HFRS)流行规律与疫源地情况,为控制HFRS流行提供依据。方法运用描述流行病和疫源地调查方法,对人间疫情和主要宿主动物进行分析,采集标本送实验室采用间接免疫荧光法检测抗体,直接免疫荧光法检测抗原。结果3年共发生294例HFRS病例,年均发病率为4.01/10万;死亡1例,病死率0.33%。散发于78个乡镇,占总乡镇数的54.55%,发病季节呈双峰型,冬春峰发病数相比1.29:1,农民发病占83.67%,男女性别比为2.54:1,20~59岁组发病占81.29%。室外鼠密度为3.64%,室内鼠密度为3.68%。褐家鼠和黑线姬鼠是室内和野外优势鼠种,带毒指数分别为0.026、0.034。3年中鼠带毒指数分别是0.048、0.036、0.032,与发病率变化存在相关性。结论衢州市3年中的HFRS发病率低、人群隐性感染率低、主要宿主的鼠带毒指数低,与全国、全省的监测情况基本一致,说明肾综合征出血热存在年代波动的自然规律性。衢州市进一步向混合型疫区转变。证实:鼠带毒指数与发病率之间存在相关性。

     

    Abstract: Objective This study was conducted to understand the epidemic mode and epidem-iC foci situation of hemorrhagic fever with renal syndrome (HFRS).SO as to provide evidence for HFRS control.Methods By applying descriptive epidemiology methods and epidemic foci sue-vey,epidemic situation among humans and the main host animals were analyzed.Samples were collected and then were sent to the laboratories.The antibody was determined by indirect im-munofluorescence assay while the antigen was determined by direct immunofluorescence assay.Results There were all together 294 HFRS cases during the 3 years and the average annual mot-bidity rate was 4.01/lakh.Besides.There was one death case and the mortality rate was 0.33%.The disease was distributed throughout 78 towns and counties.Accounting for 54.55% 0f all towns and counties in that area.The onset seasons showed a double peak mode for incidence with Deak incidence ratio of winter to spring 1.29:1.Farmers accounted for 83.67% of all patients who had the disease and the ratio of the male to the female was 2.54:1.The incidence number of group between the age 0f 20 to 59 accounted for 81.29%.Moreover.The rat density in the open air was 3.64% whereas the corresponding one indoors was 3.68%.The brown rattus andersoni and aoode-mus agrarius were predominant in rats indoors and outdoors.With toxic index of 0.026 and 0.034 respectively.The toxic indexes of rat were respectively 0.048,0.036,and 0.032 during the 3 years,correlating with the change of morbidity rate.Conclusion During the 3 years in Quzhou,HFRS morbidity,recessive infection rate among population,and the toxic index of rat for the main host. Were all JOW, which were basically the same with the surveillance situation in the province and all over the country.Indicating that the onset of HFRS was in accordance with the natural law of fluctuating with the year.Quzhou was further transformed to mixed epidemic area.Furthermore,it was verified tllat the toxic index of rat was correlated with morbidity rate.

     

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