Abstract: Objective This analysis was to learn about the situation of infection of Schistosomiasis，Malaria and Filariasis among migrants in Nanhui District of Shanghai and to provide scientific basis for monitoring of diseases. Methods Immunoenzymatic staining and triple antigen glass slide were adopted for immunoassay of schistosomiasis，malaria and filariasis，as well as blood test of plasmodia. Results In 54386 migrants undergoing quarantine，the overall positive rate of antibodies was 0.69％，of which the positive rate of antibody of schistosomiasis，malaria and filariasis was 0.24％，0.36％and 0.09％，respectively；meanwhile，2995 foreign residents were also quarantined and the positive rate was 0.13％ Conclusion Due to the vast influx of migrants from other places，the epidemic risks of schistosomiasis，malaria and filariasis still exist，hence it is necessary to strengthen the monitoring on migrants from other places，normalize management on migrants and improve the quality of monitoring.