韶关市健康人群百日咳、白喉和破伤风抗体水平监测
Monitoring on antibody levels of pertussis, diphtheria and tetanus in healthy population of Shaoguan
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摘要: 目的 了解韶关市健康人群百日咳、白喉和破伤风免疫状况,及时为免疫策略提供科学依据。方法 随机抽查部分0～4 0岁健康人群进行了百日咳、白喉和破伤风抗体水平监测。结果 百日咳抗体几何平均滴度GeimetricMeanTiter(GMT)和抗体保护率分别为1∶374 2、67.74% ;白喉、破伤风抗毒素GMT分别为0.1699IU/ml、0.1804IU/ml,阳性率分别为88.94 %、91.83%。结论 对百日咳、白喉和破伤风已经形成了较好的免疫屏障,但人群百日咳抗体水平偏低,应大力推广应用吸附无细胞百日咳、白喉、破伤风联合疫苗.Abstract: Objective This study was intended to understand the status of immunization against pertussis，diphtheria and tecanus in healthy population and provide a timely seiemitic basis for immuniza- tion strategy. Methods A number of healthy people aged between 0-40 were randomly selected to un-dergo monitoring antibody levels of pertussis,diphtheria and tetanus. Results The geometric mean titer (GMT) and rate of protection for pertussis antibody were 1:374.2 and 67.74％，respectively；GMT of diphtheria and tetanus antitoxin was 0.1699IU／ml and 0.1804IU／ml，with a positive rate of 88.94％ and 91.83％，respectively. Conclusion A good immunological barrier against pertussis，diphtheria and tetanos has formed，but the antibody level of pertussis among people is a little lower, therefore we should strongly extend the use of Adsorbed Diphtheria，Tetanus and Acellular Pertussis Combined Vaccine.
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