高志坚, 王洁, 张本旭, 郭津惠, 郭威, 单永明, 郭秀升, 刘冬梅. 德州市1989~2003年消灭脊髓灰质炎监测与控制分析[J]. 疾病监测, 2005, 20(4): 203-207. DOI: 10.3784/j.issn.1003-9961.2005.4.203
引用本文: 高志坚, 王洁, 张本旭, 郭津惠, 郭威, 单永明, 郭秀升, 刘冬梅. 德州市1989~2003年消灭脊髓灰质炎监测与控制分析[J]. 疾病监测, 2005, 20(4): 203-207. DOI: 10.3784/j.issn.1003-9961.2005.4.203
GAO Zhi-jian, WANG Jie, ZHANG Ben-xu, GUO Jin-hui, GUO Wei, SHAN Yong-ming, GUO Xiu-sheng, LIU Dong-mei. Analysis on Monitoring and Control of Elimination of Poliomyelitis from 1989 to 2003 in Dezhou City[J]. Disease Surveillance, 2005, 20(4): 203-207. DOI: 10.3784/j.issn.1003-9961.2005.4.203
Citation: GAO Zhi-jian, WANG Jie, ZHANG Ben-xu, GUO Jin-hui, GUO Wei, SHAN Yong-ming, GUO Xiu-sheng, LIU Dong-mei. Analysis on Monitoring and Control of Elimination of Poliomyelitis from 1989 to 2003 in Dezhou City[J]. Disease Surveillance, 2005, 20(4): 203-207. DOI: 10.3784/j.issn.1003-9961.2005.4.203

德州市1989~2003年消灭脊髓灰质炎监测与控制分析

Analysis on Monitoring and Control of Elimination of Poliomyelitis from 1989 to 2003 in Dezhou City

  • 摘要: 目的了解德州市脊髓灰质炎(脊灰)监测与控制系统的运转状况。方法收集1989-2003年脊灰监测数据,进行分析和评价。对AFP病例采集双份粪便标本,对部分AFP病例的接触者及健康人群采集粪便标本进行肠道病毒检测,并对2432份健康人群血清标本进行脊灰中和抗体检测。结果1991年建立急性弛缓性麻痹(AFP)监测系统以来,全市共报告AFP病例477例,1994年来非脊灰AFP报告发病率达到了WHO提出的1/10万指标,1995年以来AFP病例及时报告率、及时调查率、双份标本合格采集率、标本及时送检率和随访率均在90%以上,达到了卫生部80%的指标。脊灰疫苗(TOPV)接种率维持在90%以上,0~4岁儿童强化免疫接种率达到95%以上,1990年10月以来未发生脊灰野病毒病例。抗体检测表明,三型脊灰抗体阳性率维持在95%以上,AFP病例标本和接触者标本及健康人群肠道病毒检测,未检出脊灰病毒。结论德州市AFP监测系统运转良好,由于形成了较为牢固的脊灰人群免疫屏障,便得脊灰流行的可能性降为最低。

     

    Abstract: Objective This analysis was designed to learn about the operation of monitoring and con-trol system for poliomyelitis (PM) in Dezhou.Methods Data from 1989 tO 2003 were collected for analysis and evaluation.For AFP cases,double samples of feces were collected;for part of AFP contac-tors and healthy population,feces samples were gathered for enterovirus determination and 2 432 serum samples of healthy people were administered PM neutralization antibody testing.Results Since the es-tablishment of monitoring system for acute flaccid paralysis (AFP) in 1991,477 cases had been reported in the entire city.Since 1994. The onset rate of non-PM reporte- had been in accord with the index of 1/lakh proposed by WHO.Since 1995,the timely reporting rate,in-time investigation rate,rate 0f double specimens collection,rate of timely submission for determination and follow-up rate had all been over 90%,which attained the index of 80% stipulated by the Minister of Health.The vaccination rate of Trivalent Oral Polio Vaccine (TOPV) maintained over 90%,within which children aged between 0 and 4 years old had a vaccination rate of reinforeed immunization over 95%.Since October of 1990,no wild-type virus cases of PM had occurred.Antibody testing demonstrated that the positive antibody rate of type III PM was kept above 95%and no PM virus were detected from specimens of AFP cases.Con-tactors and healthy population in enterovirus testing.Conclusion The AFP monitoring system works well in Dezhou.Due tO the establishment of relatively strong immunization barrier among PM popula-tions,the possibility of PM epidemic is reduced tO the lOWest.

     

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