Abstract: Objective The present study was conducted to get the knowledge of epidemic char-actefisfics and changing tendency of leptospirosis in Leshan City and explore the strategies and measures to prevent and control leptospirosis．Methods By SPSS 11.0，general statistical method and chi-square test were adopted to make statistical analysis on the situation of leptospirosis inci-dence in Leshan from 1958 to 2005．Results 4 relatively big outbreaks occurred from 1958 to 1989．The epidemic period disappeared and showed a decrease tendency since 1990，however，the incidence increased a little since 2000．Since 2000，ages of onset showed a distinct retrocession tendency compared tO previous situation (X2=238.04，P<0.0001)．The incidence season showed a central tendency in September since 1991．There were regional differences in incidence，which was higher in mountain areas than plains，and higher in plains than hills．Rats are major source of in-fection in this area，and infection caused by dogs is also relatively high (13.31％)．Lcterohaemor-rhagiae group was the major epidemic bacterial group among people (63.28％)．Conclusion The incidence of leptospirosis in Leshan has not been effectively controlled and it's quite possible to have a partial outbreak in this area．To prevent epidemic outbreak of leptospirosis in Leshan City，we should take on the following strategies：1 Reinforcing the surveillance of epidemic status and source of infection；2 Training the doctors at basic level to improve diagnosis and treatment skills；3 Inoculating high-risk population in rural areas in order to prevent leptospirosis；4 Killing rats in farms．