Abstract: Objective This study was designed to understand the causes of high incidence of measles in Wuxing District of Huzhou City of Zhejiang Province in 2005 SO as to instruct the measles prevention and control work in the future．Methods An epidemiological analysis on the epidemic situation of measles in Wuxing District of Huzhou City of Zhejiang Province in 2005 was done．Results The incidence rate of measles in Wuxing District of Huzhou City of Zhejiang Province in 2005 was up to 150.95/1akh．The age group of peak incidence WaS of ages ranged from 15 to 34 years (59.06％ of the total)，and the age group of second incidence was of ages less than 8 months (10.26％ of the total)．For occupational distribution of cases，the top three were workers．Students, and children from scattered localities，while among the infected workers，62.87％ were peasant workers．For 91.94％ of people aged more than 8 months，measles vaccine inoculation was not performed or whether the inoculation had been done was not known，and among local children and floating children aged 8 months to 15 years，the vaccination rates were 49.47％ and 22.18％ respectively．Conclusion The main reason for epidemic of measles was the lOW primary vaccination rate and revaccination rate of measles vaccines．The inoculation system for floating children and entrance check system for students should be carried out so as to accelerate the primary vaccination rate and revaccination rate of measles vaccines，the monitoring for epidemic situation should be strengthened，and in regions where measles prevalence among adults is accelerating，preventive inoculation for the group of young adults without record of inoculation history should be performed tO avoid occurrence of epidemic situation．