Abstract: Objective This study was conducted to evaluate the information quality of direct network report of infectious diseases in Xinyang City and improve the timeliness, sensitivity and veracity of the case report. Methods Report cards of class B and C infectious diseases in Xinyang city in 2005 were obtained from the subsystem - Information Management System of Disease Surveillance and Report of China Information System for Disease Control and Prevention. The Excel database was derived from the system and was treated and statistically analyzed with SPSS12.0 software. Results The direct report rate covered all the hospitals at county or above levels in Xinyang City. However, the direct report rate only reached 27.14% of health centers at town. The report units were mainly general hospitals (60.31%). There were only few unverified and repeated cards all the year round. The average report time of was 1.46 d, from report to verification 0.03 d, and from diagnosis to verification 1.82 d. Conclusion The time from diagnosis to report was the major factor that influences the report timeliness most. The qualities of the report information of infectious diseases of different counties in Xinyang City were uneven. There should be regular quality evaluations of the direct network report and the analysis of the key parts that influence the report quality, so as to find out the problems in the management of direct network reporting systems of each county and direct the future work of the case report system.