Abstract: Objective This investigation was conducted to learn the behaviors related to road traffic injuries and utilization of the traffic safety protective measures among residents in Zhejiang to provide a scientific basis for the prevention and control of residents' road traffic injuries(RTIs). Methods Questionnaire survey was conducted on 7482 people aged from 15 to 69 from 30 typical counties of Zhejiang province with multi-staged cluster random sampling methods. Results Based on the questionnaires, It was found that 36.22% of motorcycle drivers or riders never wore helmets, and only 28.28% of them used seat belts regularly when driving or riding on the power-driven vehicles in the past 30 days. Males accounted for 33.10% of those who did not use any protective measures, with females constituting 22.76% of them. The rates of drunken driving, driving-in-fatigue, and non-licensed driving were 11.30%, 11.26%, and 12.78%, respectively. Conclusion Low usage of traffic safety protective measures and serious traffic violation exsisted among the inhabitants of Zhejiang Province.