Abstract: Objective This study was conducted to learn about the awareness of the clinic attendants for knowledge of AIDS/HIV, the infection of AIDS/ syphilis and the high risk behaviors of AIDS, and providing the basis for developing the policy of integrated interventions. Methods The questionnaire investigation was conducted for the clinic attendants, and the blood of patients was extracted for the serological detection of HIV/syphilis. Results 1 attendant was found positive in the HIV screening, and 38 attendants were found positive in RRR screening, accounting for 10.3%. The awareness rate of the clinic attendants for knowledge of AIDS/HIV varies from 24.7% to 79.9%. Recently in three months, 41.5% had sexual behavior with commercial sex workers, of which 48.7% have never use the condom, and 63.4% no use in the last time. 21.7% atttendants are examined with condyloma acuminatum, 18.4% with nongonococcal urethritis, 12.5% with syphilis, 20.9% with no-sexually transmitted disease, followed by gonorrhea and genital herpes. Conclusion The clinic attendants are at high risk of AIDS/HIV because of shortage of knowledge of AIDS/HIV and high risk behavior of AIDS/HIV. We should strengthen the general motoring for the clinic attendants and develop the health education further.