Abstract: Objective The study was conducted to analyze the reported incidence of notifiable infectious diseases based on the epidemiological surveillance in Dinghai District Zhoushan City from 2004 to 2006. Methods The descriptive epidemiological approach was employed. Results Cumulatively 19 kinds of 5932 cases of statutory infectious disease were reported in three years, with an average annual reported incidence of 532.73/lakh, the average annual reported mortality 0.09/lakh. As was indicated from the classification of morbidities, blood and sexually transmitted diseases accounted for 46.93%; syphilis and hepatitis B had an yearly increasing incidence contrary to gonorrhea; gastro-intestinal diseases accounted for 38.25%, 60.33% of which constituted infectious diarrhea and their incidence was rising; the incidence of dysentery declined 25.50% in 2006 compared with that in 2005; respiratory diseases accounted for 14.50%, the incidence of tuberculosis increasing year after year; perennial sporadic incidence of mumps was observed; imported malaria was the predominant arbovirus disease. Conclusion Direct network report of notifiable infectious diseases plays an essential role in facilitating the timely detection of outbreak or clusters of diseases and timely prevention and control measures. Meanwhile, multiple-year statistics of network direct report cases should be further improved to conduct precise estimation of the actual incidence of infectious diseases.