康云平, 孙宝云. 平均红细胞血红蛋白浓度对溶血性贫血的诊断价值[J]. 疾病监测, 2008, 23(6): 368-369. DOI: 10.3784/j.issn.1003-9961.2008.6.368
引用本文: 康云平, 孙宝云. 平均红细胞血红蛋白浓度对溶血性贫血的诊断价值[J]. 疾病监测, 2008, 23(6): 368-369. DOI: 10.3784/j.issn.1003-9961.2008.6.368
KANG Yun-ping, SUN Bao-yun. Diagnostic value of MCHC in hemolytic anemia[J]. Disease Surveillance, 2008, 23(6): 368-369. DOI: 10.3784/j.issn.1003-9961.2008.6.368
Citation: KANG Yun-ping, SUN Bao-yun. Diagnostic value of MCHC in hemolytic anemia[J]. Disease Surveillance, 2008, 23(6): 368-369. DOI: 10.3784/j.issn.1003-9961.2008.6.368

平均红细胞血红蛋白浓度对溶血性贫血的诊断价值

Diagnostic value of MCHC in hemolytic anemia

  • 摘要: 目的 观察平均红细胞血红蛋白浓度(MCHC)检测对溶血性贫血(HA)的诊断价值。方法 统计HA、巨幼细胞性贫血(MA)、缺铁性贫血(IDA)、小细胞HA(先天遗传小细胞或合并IDA)各30例患者外周血象平均红细胞血红蛋白量(MCH)、MCHC、平均红细胞体积(MCV)数据,以健康人群30名为对照组,比较各实验组与对照组的MCH、MCHC、MCV均值。结果 HA患者外周血象MCHC明显高于MA、IDA及对照组(IP/I<0.01);IDA患者外周血象MCHC明显低于对照组(IP/I<0.01);MA患者外周血象MCHC与对照组差异无统计学意义(IP/I>0.05),MCV明显高于对照组(IP/I<0.01);小细胞HA外周血象MCHC与对照组差异无统计学意义(IP/I>0.05),MCV明显低于对照组(IP/I<0.01)。结论 外周血象MCHC检测可作为HA的诊断指标。

     

    Abstract: Objective The study was conducted to evaluate the diagnostic value of the mean corpuscular hemoglobin concentration(MCHC) in hemolytic anemia(HA). Methods The mean corpuscular volume(MCV), mean corpuscular hemoglobin(MCH) and MCHC were compared between four experimental groups of patients and a control group of healthy people, with 30 subjects in each. Patients with iron deficiency anemia(IDA), megaloblastic anemia(MA), HA, and small cell HA (congenital small RBCs or concomitant IDA) were divided into the four experimental groups. Results HA patients had conspicuously higher MCHC than MA, IDA patients and people in the control group(IP/I0.01). IDA patients had obviously lower MCHC than people in the control group (IP/I0.01). There was no difference in MCHC between the MA group and the control group(IP/I0.05), whereas MA patients had higher MCV than people in the control group(IP/I0.01). There was no difference in MCHC between the small cell HA group and the control group(IP/I0.05), though people in the control group had higher MCV(IP/I0.01). Conclusion MCHC could be used as a diagnostic indicator of hemolytic anemia.

     

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