Abstract: ObjectiveTo investigate the current situations of metabolic syndrome (MS) as well as its components: obesity, high blood pressure, high cholesterol, high blood sugar disease, in Ruian city, Zhejiang province, and analyze related risk factors, providing evidence for the prevention, treatment and care. MethodsThe prevalence of MS was determined based on a sample of 2351 workers who received regular physical examinations. Related factors were analyzed and high-risk groups identified according to the MS risk factors, upon which the development of prevention, care and medical countermeasures were based. ResultsThe prevalence rate of MS was 11.0%, 13.6% in men and 7.6% in women. High prevalence was observed in men over the age of 30 and women above 40, and these people were classified as the high-risk group. MS-related unconditional Logistic multiple Regression analysis showed that the OR of high blood pressure was 66.869 in men and 109.13 in women, suggesting that high blood pressure was a risk factor for MS. ConclusionThe prevalence of MS was higher in men than that in women based on the subject population. Men above the age of 30 and women older than 40, as well as hypertensive groups, were at high risk of MS and its concomitant manifestations. Therefore, related medical and nursing staff should pay attention to the prevention, treatment and health education for high-risk groups; regular physical examination shall be performed to facilitate early diagnosis and intervention with a view to reducing adverse clinical prognosis.