龚晓英, 方春福, 钟建跃. 成人病毒性乙型肝炎疫苗免疫失败的行为危险因素分析[J]. 疾病监测, 2009, 24(4): 257-258. DOI: 10.3784/j.issn.1003-9961.2009.04.011
引用本文: 龚晓英, 方春福, 钟建跃. 成人病毒性乙型肝炎疫苗免疫失败的行为危险因素分析[J]. 疾病监测, 2009, 24(4): 257-258. DOI: 10.3784/j.issn.1003-9961.2009.04.011
GONG Xiao-ying, FANG Chun-fu, ZHONG Jian-yue. Analysis on behavior factors associated with failure of hepatitis B vaccination among adults  [J]. Disease Surveillance, 2009, 24(4): 257-258. DOI: 10.3784/j.issn.1003-9961.2009.04.011
Citation: GONG Xiao-ying, FANG Chun-fu, ZHONG Jian-yue. Analysis on behavior factors associated with failure of hepatitis B vaccination among adults  [J]. Disease Surveillance, 2009, 24(4): 257-258. DOI: 10.3784/j.issn.1003-9961.2009.04.011

成人病毒性乙型肝炎疫苗免疫失败的行为危险因素分析

Analysis on behavior factors associated with failure of hepatitis B vaccination among adults  

  • 摘要: 目的分析成人病毒性乙型肝炎(乙肝)疫苗(HepB)免疫失败的行为危险因素。方法对62名免后乙肝病毒表面抗体(抗-HBs)几何浓度(GMC)10 mIU/ml的免疫失败者与对照组以年龄、性别、职业为配对条件,1∶1对比调查吸烟、饮酒、拔牙和手术史,计算IOR、/I95%可信限和IP/I值。结果免疫失败组吸烟率高于对照组,差异有统计学意义(IP/I<0.05),而饮酒、拔牙和手术史两组间比较差异均无统计学意义。结论吸烟是HepB免疫失败的主要危险因素。

     

    Abstract: ObjectiveTo analyze the behavior factors associated with the failure of hepatitis B vaccination among adults. MethodsA 1∶1 case control study matched by age, gender and occupation was conducted for 62 people whose GMC of anti-NBs10 mIU/ml, which included the interview about the histories of smoking, alcohol use, dental surgery and general surgery for both groups, the odds ratio (IOR/I), 95% confidence limit and IP/I value were calculated. ResultsThe cigarette smoking rate was higher in vaccination failure group than in control group, the difference was of statistical significance (IP/I<0.05), while the difference on the histories of alcohol use, dental surgery and general surgery had no statistical significance. ConclusionCigarette smoking was the main risk factors for the failure of hepatitis B vaccination.

     

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