Abstract: ObjectiveTo evaluate the capability of BIOMIC antimicrobial susceptibility analyzing system to interpret the minimal inhibitory concentration (MIC) of methicillin-resistant IS. aureus/I (MRSA). MethodsA total of 50 strains of MRSA were tested for their sensitivity to 10 different antibiotics via disk diffusion method. The results were interpreted by BIOMIC antimicrobial susceptibility analyzing system, and compared with the results obtained from Etest with the software of WHONET5.4. The ratio of MIC obtained from BIOMIC system and that measured via Etest method were calculated to evaluate the consistency of these two methods. ResultsGentamycin MIC (S, I, R) obtained from the two methods showed a consistency of 98.00%, with an error rate of 2.00%. MIC of other antibiotics (S, I, R) exhibited 100% consistency between the two methods. Based on the BIOMIC MIC/Etest MIC ratio, the total consistency of MIC was 83.92%. ConclusionBIOMIC analyzing system and Etest method show good consistency in testing MRSA, especially in testing sensitive strains. BIOMIC can be used to do preliminary judgments in clinical test for drug resistance or resistance surveillance.