王乐见, 李招云, 史春娟, 张黎明, 沈景丰. 2913例妇女生殖道人乳头瘤病毒感染筛查分析[J]. 疾病监测, 2009, 24(11): 849-851. DOI: 10.3784/j.issn.1003-9961.2009.11.013
引用本文: 王乐见, 李招云, 史春娟, 张黎明, 沈景丰. 2913例妇女生殖道人乳头瘤病毒感染筛查分析[J]. 疾病监测, 2009, 24(11): 849-851. DOI: 10.3784/j.issn.1003-9961.2009.11.013
WANG Le-jian*, LI Zhao-yun, SHI Chun-juan, ZHANG Li-ming, SHEN Jing-feng. Screening analysis of 2913 cases of HPV infection of the genital tract[J]. Disease Surveillance, 2009, 24(11): 849-851. DOI: 10.3784/j.issn.1003-9961.2009.11.013
Citation: WANG Le-jian*, LI Zhao-yun, SHI Chun-juan, ZHANG Li-ming, SHEN Jing-feng. Screening analysis of 2913 cases of HPV infection of the genital tract[J]. Disease Surveillance, 2009, 24(11): 849-851. DOI: 10.3784/j.issn.1003-9961.2009.11.013

2913例妇女生殖道人乳头瘤病毒感染筛查分析

Screening analysis of 2913 cases of HPV infection of the genital tract

  • 摘要: 目的了解浙江省台州地区妇女感染人乳头瘤病毒(HPV)和年龄分布,以及各亚型与宫颈病变的关系。 方法采用聚合酶链反应扩增结合DNA芯片反向点杂交技术,对来浙江省台州市中心医院妇科就诊的2913例患者进行生殖道HPV亚型检测。结果HPV总感染率35.08%,检出前5位依次为HPV16(占7.76%)、HPV11(占7.38%)、HPV52(占6.25%)、HPV33(占4.81%)、HPV58(占4.50%)。结论台州地区妇女生殖道HPV人群感染年龄主要分布在40岁以下,以高危型为主,与宫颈病变的发生密切相关。

     

    Abstract: ObjectiveThe study was conducted to evaluate the prevalence of Human papillomavirus(HPV) infection among women in Taizhou, Zhejiang province, and determine the age distribution and the correlation of different subtypes with cervical lesions. MethodsPCR amplification and reverse dot blot DNA chip technology were employed to identify the HPV subtypes for 2913 cases of HPV infection of the genital tract that visited the central gynecological hospital in Taizhou. ResultsThe overall HPV infection rate was 35.08%, the top five subtypes with the highest rates including HPV16(7.76%), HPV11(7.38%), HPV52(6.25%), HPV33(4.81%) and HPV58(4.50%). ConclusionHPV infections were primarily prevalent in the age group under forty years old, of which high-risk HPV infections were prominent, suggesting high correlation between the infection and the onset of cervical lesions.

     

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