Abstract: Response to the communicable diseases prevalence is never a matter of one independent country. Mutual impacts along with the economical globalization in the various countries ask the whole world to be an integrated body to pay attention together, face the challenge together, and cooperate fully on disease prevention and control. In front the challenge of A/H1N1 outbreak, the development of international cooperation is essential regarding to promote the implementation of A/H1N1 flu strategy, information's fast and wide-ranging dissemination and use, disease surveillance and manpower training and ability enhance.