张海艳, 周艳丽, 马立宪, 徐文彩, 戴威, 翟力军, 赵丽英. 北京市东城区乙型病毒性肝炎血清流行病学调查[J]. 疾病监测, 2010, 25(7): 531-533. DOI: 10.3784/j.issn.1003-9961.2010.07.008
引用本文: 张海艳, 周艳丽, 马立宪, 徐文彩, 戴威, 翟力军, 赵丽英. 北京市东城区乙型病毒性肝炎血清流行病学调查[J]. 疾病监测, 2010, 25(7): 531-533. DOI: 10.3784/j.issn.1003-9961.2010.07.008
ZHANG Hai-yan, ZHOU Yan-li, MA Li-xian, XU Wen-cai, DAI Wei, ZHAI Li-jun, ZHAO Li-ying. Seroepidemiological survey of hepatitis B in Dongcheng district, Beijing[J]. Disease Surveillance, 2010, 25(7): 531-533. DOI: 10.3784/j.issn.1003-9961.2010.07.008
Citation: ZHANG Hai-yan, ZHOU Yan-li, MA Li-xian, XU Wen-cai, DAI Wei, ZHAI Li-jun, ZHAO Li-ying. Seroepidemiological survey of hepatitis B in Dongcheng district, Beijing[J]. Disease Surveillance, 2010, 25(7): 531-533. DOI: 10.3784/j.issn.1003-9961.2010.07.008

北京市东城区乙型病毒性肝炎血清流行病学调查

Seroepidemiological survey of hepatitis B in Dongcheng district, Beijing

  • 摘要: 目的 了解和分析北京市东城区1~59岁人群乙型病毒性肝炎(乙肝)病毒感染情况及乙肝疫苗免疫情况;探讨东城区乙肝病毒感染的影响因素;为制定防治策略提供参考。 方法 采用多阶段抽样方法,抽取东城区3个调查点1~59岁常住人口共593人,进行血清流行病学调查。 结果 东城区1~59岁人群乙肝病毒表面抗原(HBsAg)标化阳性率为4.57%,乙肝病毒核心抗体(抗-HBc)标化阳性率为26.03%;乙肝病毒表面抗体(抗-HBs)标化阳性率为44.88%,乙肝疫苗接种率为57.84%;14岁人群HBsAg阳性率为1.05%,抗-HBc阳性率为2.46%;抗-HBs阳性率为62.23%;乙肝疫苗接种率为97.54%;影响乙肝HBsAg阳性率的3大主要因素为家族中有无乙肝携带者、是否接种乙肝疫苗、是否经常去洗浴场所修脚。 结论 东城区在实施乙肝疫苗计划免疫管理后,人群乙肝携带率明显下降。

     

    Abstract: Objective To determine the infection prevalence and immunization coverage of viral hepatitis B among the population aged from 1 to 59 in Dongcheng district, Beijing, and to identify the risk factors of the infection in this region, providing the basis for development of control strategies. Methods A multi-stage sampling method was used to carry out serological surveys for 593 resident subjects aged from 1 to 59 in Dongcheng district. Results For the surveyed population, the standardized seroprevalence of HBsAg, anti-HBc and anti-HBs was 4.57%,26.03% and 44.88%, respectively; the immunization coverage rate was 57.84%. For those aged 14 years or below, the seroprevalence of HBsAg, anti-HBc and anti-HBs was 1.05%, 2.46% and 62.23%, respectively, with an immunization coverage rate of 97.54%. The three major risk factors for HBsAg positivity were the presence of a HBV-carrying family member, history of receiving HBV vaccines and frequent visits for pedicure bath. Conclusion After the implementation of the expanded program on immunization of HBV, the virus-carrying population in Dongcheng district reduced noticeably.

     

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