Abstract: Objective To analyze the follow-up of HIV/AIDS cases in 2008 and evaluate the data quality. Methods The HIV/AIDS case reporting cards and follow-up cards in 2008 which were obtained from national HIV/AIDS database in January 2009 were analyzed. Results By the end of 2008,of all reported people living with HIV/AIDS,44.1% were followed up. The demographic features of those with low follow-up rate were male,unmarried,15-34 year old,being engaged in public service and minority ethnic groups of Yi and Uygur. The follow-up rate of those infected by injecting drug use was low (32.7%). Among the HIV/AIDS cases followed up,7.4% still had unsafe sexual behaviors after the first follow up. Data missing and logic errors existed on the intervention and aid items in the follow up cards. Conclusion It is important to conduct follow-up among people living with HIV/AIDS cases who are sexually active,intravenous drug users and people in minority ethnic groups of Yi and Uygur in the future,and it is necessary to improve the quality of reported data about follow up.