Abstract: Objective To evaluate the current status, problem still existed and related factors in routine immunization coverage reporting in Zhejiang. Methods The surveillance data of routine immunization since 2005 were analyzed. Results The immunization coverage rates of BCG,OPV,DPT,MV and HBV ranged from 97.74% to 99.99%. The analysis of difference value and ratio value showed that reported immunization coverage rates of most vaccines during 2005 - 2009 were reliable, except BCG and MV. The investigated immunization coverage rates of all vaccines of local children were higher than those of children in floating population. The revised vaccination rates of full immunization series were above 90% in each year and increased by years. Conclusion The surveillance system of routine immunization in Zhejiang province had become more stable, and the surveillance quality was improved by years. It is essential to strengthen the management of vaccination in children among floating population to improve the surveillance of routine immunization quality.