沈国平, 姚娟, 李海雁, 邢建明. 浙江省湖州市婚检人群艾滋病、梅毒、乙型病毒性肝炎检测分析[J]. 疾病监测, 2011, 26(8): 626-628. DOI: 10.3784/j.issn.1003-9961.2011.08.013
引用本文: 沈国平, 姚娟, 李海雁, 邢建明. 浙江省湖州市婚检人群艾滋病、梅毒、乙型病毒性肝炎检测分析[J]. 疾病监测, 2011, 26(8): 626-628. DOI: 10.3784/j.issn.1003-9961.2011.08.013
SHEN Guo-ping, YAO Juan, LI Hai-yan, XING Jian-ming. Detections of HIV, syphilis and HBV infections in premarital medical examination in Huzhou, Zhejiang province[J]. Disease Surveillance, 2011, 26(8): 626-628. DOI: 10.3784/j.issn.1003-9961.2011.08.013
Citation: SHEN Guo-ping, YAO Juan, LI Hai-yan, XING Jian-ming. Detections of HIV, syphilis and HBV infections in premarital medical examination in Huzhou, Zhejiang province[J]. Disease Surveillance, 2011, 26(8): 626-628. DOI: 10.3784/j.issn.1003-9961.2011.08.013

浙江省湖州市婚检人群艾滋病、梅毒、乙型病毒性肝炎检测分析

Detections of HIV, syphilis and HBV infections in premarital medical examination in Huzhou, Zhejiang province

  • 摘要: 目的 了解浙江省湖州市婚检人群中艾滋病、梅毒和乙型病毒性肝炎(乙肝)的感染情况并作必要性探讨。 方法 对2008年5月至2010年12月到浙江省湖州市妇幼保健院进行婚前医学检查人群进行乙肝病毒表面抗原(HBsAg)、梅毒抗体及人类免疫缺陷病毒抗体(抗-HIV)检测。 结果 21 831名婚检人群中,HBsAg阳性居首位,占4.65%;其次是梅毒抗体阳性,占0.30%;再次是抗-HIV阳性,占0.009%。男、女性HBsAg阳性率差异有统计学意义,男性高于女性(2=46.63,P0.05);男、女性梅毒阳性率差异无统计学意义(2=0.38,P0.05)。2008 - 2010年HBsAg阳性率有逐渐下降趋势,各年间差异无统计学意义(2=3.93,P0.05);梅毒抗体阳性率有逐渐上升趋势,各年间差异有统计学意义(2=10.44,P0.05);从乙肝三系检测结果看,HBeAg阳性占20.95%,主要为HBsAg+HBeAg+抗-HBc和HBsAg+抗-HBe+抗-HBc两种模式,占83.82%。 结论 湖州市婚检人群HBsAg、梅毒、HIV感染率不高,但婚检人群作为特殊人群,应引起特别关注;婚前医学检查对疾病控制、普及传染病预防知识、提高生活质量、保障家庭幸福及提高出生人口素质有重要意义。

     

    Abstract: Objective To understand the current status of HIV, syphilis and HBV infections in population receiving premarital medical examination in Huzhou. Methods HBsAg, syphilis antibody and HIV antibody were detected among people receiving premarital medical examination in our hospital from May 2008 to December 2010. Results Among 21 831 people surveyed, 4.65% were detected to be HBsAg positive, 0.30% were syphilis positive and 0.009% were HIV positive. The HBsAg positive rate was higher in males than in females, the difference was statistically significant(2=46.63,P0.05). No significant difference was found on syphilis positive rate between males and females(2=0.38,P0.05).The HBsAg positive rate decreased with years from 2008 to 2010, no significant differences were found among these years(2=3.93,P0.05). The syphilis positive rate increased with years, statistically significant differences were found among these years(2=10.44,P0.05).For HBV detection, 20.95% were HBeAg positive. Two main infection models were found: HBsAg+HBeAg+HBcAb and HBsAg+HBeAb+HBcAb, accounting for 83.82%. Conclusion The positive rates of HBsAg, syphilis and HIV in the population receiving premarital medical examination were not high in Huzhou, but as a special population, it is necessary to pay close attention to them. Premarital medical examination would play an important role in disease control, education about communicable disease prevention, improving life quality, ensuring family happiness and improving population quality.

     

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