Abstract: Objective To describe the clinical and epidemiological features of listeriosis in China from 2000 to 2009 and provide evidence for improvement of listeriosis prevention and control. Methods The literatures about listeriosis in China from 2000 to 2009 were collected through electronic and manual search to conduct clinical and epidemiological analysis of listeriosis were included. Results A total of 92 clinical cases of listeriosis, including 54 cases in perinatal stage and 63 cases in non-perinatal stage. The main clinical manifestation of listeriosis was septicemia (39%). The patients in pregnancy were more likely (91%) to have fever (37.5-40 ℃). The average case fatality among the cases analyzed was 21% (19/89), but the case fatality in the neonates was as high as 56% (14/25). Cases were reported in half of the provinces in China, but most often (57%) in Shanghai and Beijing. Conclusion The clinical and epidemiological features and case fatality of listeriosis in China were similar to those in European and American countries.