崔晶花, 杨小蓉, 杜小莉, 王鸣柳, 崔志刚, 李伟. 60株克罗诺杆菌的药敏分析[J]. 疾病监测, 2012, 27(5): 409-411. DOI: 10.3784/j.issn.1003-9961.2012.5.023
引用本文: 崔晶花, 杨小蓉, 杜小莉, 王鸣柳, 崔志刚, 李伟. 60株克罗诺杆菌的药敏分析[J]. 疾病监测, 2012, 27(5): 409-411. DOI: 10.3784/j.issn.1003-9961.2012.5.023
CUI Jing-hua, YANG Xiao-rong, DU Xiao-li, WANG Ming-liu, CUI Zhi-gang, LI Wei. Drug susceptibility of 60 strains of Cronobacter spp.[J]. Disease Surveillance, 2012, 27(5): 409-411. DOI: 10.3784/j.issn.1003-9961.2012.5.023
Citation: CUI Jing-hua, YANG Xiao-rong, DU Xiao-li, WANG Ming-liu, CUI Zhi-gang, LI Wei. Drug susceptibility of 60 strains of Cronobacter spp.[J]. Disease Surveillance, 2012, 27(5): 409-411. DOI: 10.3784/j.issn.1003-9961.2012.5.023

60株克罗诺杆菌的药敏分析

Drug susceptibility of 60 strains of Cronobacter spp.

  • 摘要: 目的 研究国内分离于11个省(直辖市)婴幼儿配方奶粉或米粉等食品标本中的60株克罗诺杆菌的药物敏感性和耐药性。 方法 采用Kirby-Bauer纸片扩散法测定菌株对7类14种抗生素的药敏情况。 结果 菌株对头孢吡肟、亚胺培南、美罗陪南平、环丙沙星、复方新诺明5种抗生素的敏感率较高,达到93.5%。但有4株菌对14种抗生素全部耐药,4株菌对头孢呋辛耐药,1株菌对阿莫西林/克拉维酸耐药。 结论 60株克罗诺杆菌中,56株菌对目前医院内治疗肠杆菌科感染的多数抗生素药物敏感;4株菌具有强耐药性,其耐药机制需要今后进一步研究证实。

     

    Abstract: Objective To study the drug susceptibility of Cronobacter spp. isolated from the infant powdered formula and rice flour in 11 provinces. Methods The drug susceptibility test of 60 strains of Cronobacter spp. was conducted with disk diffusion method. Results Most strains (93.5%) were sensitive to cefepime, imipenem, meropenem, ciprofloxacin and trimethoprim-sulfamethoxazole, but 4 strains were resistant to all the antibiotics used in this study, four strains were resistant to cefuroxime and 1 strain was resistant to amoxicillin-clavulanic acid. Conclusion Among 60 strains of Cronobacter spp. in this study, 56 were sensitive to most antibiotics used for Enterobacter infection in hospitals, 4 were highly resistant. The further study is needed to understand the resistant mechanism of these strains.

     

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