北京市东城区1~12岁健康儿童流感嗜血杆菌携带状况调查

Carriage of Haemophilus influenzae among healthy children aged 1-12 years in Dongcheng district, Beijing

摘要: 目的了解北京市东城区1~12岁健康儿童流感嗜血杆菌携带状况。方法选取北京市东城区1~12岁健康儿童221名,每季度采集鼻咽拭子标本1次,进行流感嗜血杆菌培养、血清分型及耐药性检测。结果东城区1~12岁健康儿童流感嗜血杆菌分离率为8.75%,累计携带率为29.41%,b型流感嗜血杆菌结合疫苗接种率为5.24%。结论 1~12岁儿童存在着一定流感嗜血杆菌疾病的风险,有必要建立科学的监测体系,研制出适合国情的流感嗜血杆菌疫苗。

Abstract: Objective understand the carriage status of Haemophilus influenzae among healthy children aged 1-12 years in Dongcheng district, Beijing. Methods Nasopharageal swabs were collected from 221 healthy children aged 1-12 years randomly selected in Dongcheng district every three months to isolate H. influenzae. Results The isolation rate of H. influenzae was 8.75%,and the cumulative carrying rate was 29.41%. The coverage of H. influenzae b conjugate vaccine was 5.24%. Conclusion It is necessary to establish scientific surveillance system and develop appropriate H. influenzae vaccine.