Abstract: Objective To understand the epidemiological characteristics of hemorrhagic fever with renal syndrome (HFRS) in Jinzhou and provide evidence for the prevention and control of HFRS. Methods Descriptive epidemiological analysis was conducted on the incidence data of HFRS in Jinzhou from 1982 to 2012. Results A total of 5142 HFRS cases were reported during this period, including 55 deaths. The average annual incidence was 5.57/lakh and case fatality rate was 1.07%. The disease had a spread trend from adjacent counties to urban area, the cases were reported in all 7 counties (district). The incidence peaked during March-May. The cases mainly occurred in age group 30-49 years and most cases were farmers. Conclusion The incidence of HFRS showed a low-up-down-low and stable trend in Jinzhou from 1982 to 2012. The epidemic has been under effective control.