Abstract: Objective To understand the causes and characteristics of pesticide poisoning in Yuhang, Hangzhou municipality, and provide scientific evidence for the prevention and control of pesticide poisoning. Methods The incidence data of pesticide poisoning in Yuhang from 2006 to 2012 were collected and analyzed with SPSS13.0. Results A total of 825 cases of pesticide poisoning, including 32 deaths, were reported during this period, in which 130, including 3 deaths, belonged to occupational poisoning, 695 belonged to non-occupational poisoning. Among non-occupational poisoning cases, 601, including 29 deaths, were suicide cases (90.6%). Occupational poisoning and mis-taking of pesticide mainly occurred in males, but suicide mainly occurred in females. The majority of occupational poisoning occurred in age group 50 years, while the suicide mainly occurred in age groups18 years, 30 years and 40 years, and mis-taking of pesticide mainly occurred in age groups 18 years and 60 years. Occupational poisoning mainly occurred in the third quarter, but non-occupational poisoning had no obvious seasonality. Many kinds of pesticides were involved, including those which are prohibited to use in China. Conclusion Pesticide poisoning has become a public health threat to local people. Comprehensive measures need to be taken for the management and control of pesticide. In addition, more attention should be paid to the mental health of young adults, females and the elderly.