余坚, 陈俐丽, 谢奇朋, 何时军. 浙江省温州市儿童肺炎支原体流行特征分析[J]. 疾病监测, 2013, 28(2): 122-125. DOI: 10.3784/j.issn.1003-9961.2013.2.011
引用本文: 余坚, 陈俐丽, 谢奇朋, 何时军. 浙江省温州市儿童肺炎支原体流行特征分析[J]. 疾病监测, 2013, 28(2): 122-125. DOI: 10.3784/j.issn.1003-9961.2013.2.011
YU Jian, CHEN Li-li, XIE Qi-peng, HE Shi-jun. Characteristics of Mycoplasma pneumoniae infection among children in Wenzhou, Zhejiang[J]. Disease Surveillance, 2013, 28(2): 122-125. DOI: 10.3784/j.issn.1003-9961.2013.2.011
Citation: YU Jian, CHEN Li-li, XIE Qi-peng, HE Shi-jun. Characteristics of Mycoplasma pneumoniae infection among children in Wenzhou, Zhejiang[J]. Disease Surveillance, 2013, 28(2): 122-125. DOI: 10.3784/j.issn.1003-9961.2013.2.011

浙江省温州市儿童肺炎支原体流行特征分析

Characteristics of Mycoplasma pneumoniae infection among children in Wenzhou, Zhejiang

  • 摘要: 目的 分析浙江省温州市儿童肺炎支原体感染趋势及流行特征。 方法 采用酶联免疫吸附试验(enzyme-linked immunosorbent assay,ELISA)检测20 385例疑似肺炎支原体感染患儿血清肺炎支原体IgM抗体,并对结果进行回顾性分析。以每半个月为肺炎支原体流行监测的一个监测时间点,从2007年1月开始连续监测至2012年7月,通过肺炎支原体IgM抗体阳性率变化来分析肺炎支原体感染趋势及流行特征。 结果 2007年1月至2012年7月期间温州市儿童肺炎支原体感染分别在2007年1月上半月(阳性率55.17%)、2009年10月下半月(阳性率54.10%)出现高峰,在2007年12月下半月(阳性率12.24%)、2011年8月下半月(阳性率10.70%)出现低谷;2009年、2010年度内的大多数监测时间点其阳性率高于30%,特别是从2009年4月至2010年8月阳性率持续维持在30%以上;而2008、2011、2012年度内仅有若干个不连续的监测时间点其阳性率高于30%。2007年1月至2012年7月肺炎支原体IgM抗体总阳性率为28.82%;男、女性患儿阳性率分别为25.56%和34.33%,差异有统计学意义(χ2=178.39,Pχ2=390.93,P结论 血清肺炎支原体IgM抗体检测可作为肺炎支原体感染及流行监测指标;肺炎支原体IgM抗体阳性率超过50%或连续3个监测时间点阳性率超过30%可提示肺炎支原体暴发流行;温州地区在2007年初及2009-2010年曾暴发流行过肺炎支原体,预计在2013年或2014年将有可能再次暴发。

     

    Abstract: Objective To investigate the Mycoplasma pneumoniae (MP) infection status among children in Wenzhou, Zhejiang province. Methods MP IgM antibodies in serum of 20 385 children with suspected Mycoplasma pneumoniae infection were detected by using enzyme linked immunosorbent assay (ELISA) and a retrospective analysis of results was conducted. Consecutive Mycoplasma pneumoniae infection surveillance was conducted every half month from January 2007 to July 2012. The infection trend and characteristics were analyzed by using the data of MP IgM antibody positive rate. Results Mycoplasma pneumoniae infection peaks occurred in January 2007 and October 2009. Mycoplasma pneumoniae infection troughs were in December 2007 and August 2011. In 2009 and 2010, the positive rates in most consecutive surveillance were over 30%, but in 2008,2011 and 2012, the positive rates in some surveillance were over 30%. The overall positive rate of MP IgM antibidy from January 2007 to July 2012 was 28.82%, while positive rates in boy and girl were 25.56% and 34.33% respectively, the difference was statistically significant (χ2=178.39, Pχ2=390.93,PMycoplasma pneumoniae infection. Conclusion The overall Mycoplasma pneumoniae IgM antibody positive rate can be used as surveillance indicator of Mycoplasma pneumoniae infection epidemic. Positive rate>50% or positive rate>30% in consecutive surveillance indicate that a Mycoplasma pneumoniae infection epidemic would has occurred. Mycoplasma pneumoniae infection epidemic occurred in 2007, 2009 and 2010 and might occur in 2013 and 2014 in Wenzhou.

     

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