贾铮, 郭卫东, 李春英. 2010-2012年内蒙古呼和浩特市儿童轮状病毒腹泻病监测分析[J]. 疾病监测, 2013, 28(7): 536-540. DOI: 10.3784/j.issn.1003-9961.2013.7.007
引用本文: 贾铮, 郭卫东, 李春英. 2010-2012年内蒙古呼和浩特市儿童轮状病毒腹泻病监测分析[J]. 疾病监测, 2013, 28(7): 536-540. DOI: 10.3784/j.issn.1003-9961.2013.7.007
JIA Zheng, GUO Wei-dong, LI Chun-ying. Surveillance of rotavirus infection among children with diarrhea in Hohhot, 2010-2012[J]. Disease Surveillance, 2013, 28(7): 536-540. DOI: 10.3784/j.issn.1003-9961.2013.7.007
Citation: JIA Zheng, GUO Wei-dong, LI Chun-ying. Surveillance of rotavirus infection among children with diarrhea in Hohhot, 2010-2012[J]. Disease Surveillance, 2013, 28(7): 536-540. DOI: 10.3784/j.issn.1003-9961.2013.7.007

2010-2012年内蒙古呼和浩特市儿童轮状病毒腹泻病监测分析

Surveillance of rotavirus infection among children with diarrhea in Hohhot, 2010-2012

  • 摘要: 目的 研究呼和浩特地区5岁以下儿童腹泻轮状病毒(Rotavirus, RV)的流行病学特征及病毒基因亚型特点。 方法 采集内蒙古妇幼保健医院2010年7月至2012年6月所有≤59月龄的住院腹泻患儿粪便标本789份。采用酶联免疫吸附试验(ELISA)检测RV,抗原阳性标本以反转录-聚合酶链反应 (RT-PCR)方法做基因亚型检测。最后整理数据,应用SPSS 13.0统计软件进行统计分析。 结果 共检测789份粪便标本,ELISA法检出阳性288份,阳性率为36.50%。轮状病毒腹泻的主要流行月份为10月至次年2月,12~23月龄组感染率最高为50.00%,2岁以下患儿占全部患儿总数的95.83%。轮状病毒G血清亚型检测中,2010 2011年以G3亚型为主,占37.6%,2011 2012年以G9亚型为主,占67.3%;轮状病毒P基因亚型检测中,2010 2012年以P8亚型为主。 结论 轮状病毒是引起呼和浩特地区婴幼儿腹泻的主要病原之一,流行优势毒株发生了从G3到G9的转变。

     

    Abstract: Objective To understand the epidemiological characteristics of rotavirus infection and genotype characteristics of the virus in children aged less than 5 years in Hohhot. Methods Totally 789 stool specimens were collected from ≤59 months old children with diarrhea from July 2010 to June 2012. Rotavirus was detected by using ELISA, strain characterization was carried out with nested PCR. SPSS 13.0 was used to analyze the results. Results Among the samples, 288 were rotavirus antigen positive (36.50%). The incidence of rotavirus infection peaked during October-February. Rotavirus was mostly detected in children aged from 12 to 23 months. The cases in children aged Conclusion Rotavirus were one of the most common pathogen of acute gastroenteritis among infants in Hohhot.. There was a drift of predominant serotype from G3 to G9 during 2010 to 2012.

     

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