Abstract: In vegetable greenhouse, multi hazardous substances might exist due to the narrow space, high temperature, high humidity and the use of various fertilizers and pesticides, long term exposure to this microenvironment might pose threat to human health. This paper summarizes the progress in the research of hazardous factors existing in greenhouse and the impact on human health in terms of microclimate, biological factors and chemical factors to provide evidences to reduce the risk exposure in greenhouse and protect greenhouse workers' health.