Abstract: Objective To understand the incidence of chronic and non-communicable diseases in Taizhou, Zhejiang province,and provide evidence for the prevention and control of chronic diseases. Methods Descriptive epidemiologic analysis was conducted by using the prevalence data of chronic diseases in Taizhou in 2013, collecting from Zhejiang Provincial Chronic Disease Surveillance System. Results The overall incidence of four chronic diseases (diabetes, stroke, cancer and acute coronary disease) was 1119.19/lakh, and the gender specific incidence was 1133.06/lakh in males and 1104.56/lakh in females, the difference was statistical significant (P0.05). The incidence of diabetes was highest, followed by stroke, cancer and acute coronary disease. The incidence increased with age. Except diabetes, the incidence of other three chronic diseases were high in males than in females. The incidence was 1216.53/lakh in urban area and 1084.01/lakh in rural area. The difference was statistical significant (P0.05). Conclusion The incidence of chronic diseases is associated with age, gender and living area. Close attention should be paid to the prevention and control of diabetes and cancer. Old people and males are at high risk for chronic diseases.