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孟德敬, 耿坤, 王秀云, 白云, 徐志鑫, 张倩. 北京市昌平区成年人TG/HDL-C水平与糖尿病和糖尿病前期患病关系的研究[J]. 疾病监测, 2016, 31(4): 329-333. DOI: 10.3784/j.issn.1003-9961.2016.04.016
引用本文: 孟德敬, 耿坤, 王秀云, 白云, 徐志鑫, 张倩. 北京市昌平区成年人TG/HDL-C水平与糖尿病和糖尿病前期患病关系的研究[J]. 疾病监测, 2016, 31(4): 329-333. DOI: 10.3784/j.issn.1003-9961.2016.04.016
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MENG De-jing, GENG Kun, WANG Xiu-yun, BAI Yun, XU Zhi-xin, ZHANG Qian. Relationship between triglyceride to high density lipoprotein cholesterol ratio and prevalence of diabetes and prediabetes in adults in Changping district, Beijing[J]. Disease Surveillance, 2016, 31(4): 329-333. DOI: 10.3784/j.issn.1003-9961.2016.04.016
Citation: MENG De-jing, GENG Kun, WANG Xiu-yun, BAI Yun, XU Zhi-xin, ZHANG Qian. Relationship between triglyceride to high density lipoprotein cholesterol ratio and prevalence of diabetes and prediabetes in adults in Changping district, Beijing[J]. Disease Surveillance, 2016, 31(4): 329-333. DOI: 10.3784/j.issn.1003-9961.2016.04.016
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北京市昌平区成年人TG/HDL-C水平与糖尿病和糖尿病前期患病关系的研究

Relationship between triglyceride to high density lipoprotein cholesterol ratio and prevalence of diabetes and prediabetes in adults in Changping district, Beijing

    摘要
  • 摘要: 目的 分析北京市昌平区成年人甘油三酯/高密度脂蛋白胆固醇(TG/HDL-C)水平与糖尿病和糖尿病前期患病的关系。方法 研究对象为参加2013年北京市昌平区卫生与人群健康状况调查的18~79 岁昌平区常住居民。研究对象个人信息通过问卷调查获得。根据TG/HDL-C在人群中分布情况, 对男性及女性TG/HDL-C分别按照四分位数法分组。研究结局包括糖尿病、糖尿病前期以及糖尿病和糖尿病前期。结果 调查对象3895人, 其中男性1745人, 女性2150人。调查结果显示, 糖尿病患者、糖尿病前期人群、糖尿病和糖尿病前期患者分别为413、 1016 和1429人。经多因素logistic模型分析, 在男性人群中, 与0.66组相比, 1.08~1.74组和1.75组糖尿病患病风险OR值 (95%CI)分别为2.23(1.35~3.68)和2.36(1.43~3.91);糖尿病和糖尿病前期患病风险OR值 (95%CI)分别为1.38(1.01~1.87)和1.80(1.32~2.45);1.75组糖尿病前期患病风险OR值(95%CI)为1.58(1.13~2.21)。在女性人群中, 与0.57组相比, 0.83~1.30组和1.31组糖尿病患病风险OR值 (95%CI)分别为2.65(1.56~4.49)和3.72(2.23~6.22);糖尿病前期患病风险OR值(95%CI)分别为1.60(1.16~2.20)和2.20(1.59~3.04);糖尿病和糖尿病前期病患病风险OR值 (95%CI)分别为1.78(1.32~2.39) 和2.55(1.88~3.44)。结论 随着TG/HDL-C水平的增加, 糖尿病患病风险以及糖尿病前期患病风险均逐渐升高。

     

    Abstract: Objective To examine the association between triglyceride to high density lipoprotein cholesterol (TG/HDL-C) ratio and prevalence of diabetes and prediabetes in adults in Changping district, Beijing. Methods Data were collected from Changping Health and Population Health Status Survey in 2013 with a standard questionnaire. Participants aged 18-79 years were divided into four groups according to quartiles of TG/HDL-C ratio in men and women, respectively. The outcome included diabetes, prediabetes and diabetes/prediabetes. Results A total of 3895 participants (1745 men and 2150 women) were eligible for final data analysis. A total of 413 adults with diabetes, 1016 adults with prediabetes, and 1429 adults with diabetes/prediabetes were recorded in the investigation. Multivariate logistic regression analysis indicated that the odds ratio (OR) of diabetes was 2.23 (95%CI: 1.35-3.68) and 2.36 (95%CI: 1.43-3.91), respectively, and the OR of diabetes/prediabetes was 1.38 (95%CI:1.01-1.87) and 1.80 (195%CI: 1.32-2.45), respectively, in men with TG/HDL-C ratio of 0.83-1.30 and 1.31, and the OR of prediabetes was 1.58 (95%CI: 1.13-2.21) in men with TG/HDL-C ratio 1.75 compared with men with TG/HDL-C ratio 0.66. In women, the OR of diabetes in those with TG/HDL-C ratio of 0.83-1.30 and 1.31 was 2.65 (95%CI: 1.56-4.49) and 3.72 (95%CI: 2.23-6.22) respectively, the OR of prediabetes was 1.60 (95%CI: 1.16-2.20) and 2.20 (95%CI: 1.59-3.04) respectively, and the OR of diabetes/prediabetes was 1.78 (95%CI:1.32-2.39) and 2.55 (95%CI:1.88-3.44) respectively compared with those with TG/HDL-C ratio 0.57. Conclusion Increased TG/HDL-C ratio was significantly associated with increased risk of prevalence of both diabetes and prediabetes.

     

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