Abstract: Objective To understand the pattern of deaths caused by cardio-cerebral vascular diseases in urban residents in Jinzhou and provide scientific evidence for the disease prevention and control. Methods The death causes were classified according to the ICD-10 and the standardized mortality was calculated according to the data of national population census in 2010. The potential years of life lost (YPLL), the rate of potential years of life lost (YPLLR) and the average years of life lost (AYLL) due to major cardio-cerebral vascular diseases were calculated. Results The overall mortality rate of cardio-cerebral vascular diseases in urban residents in Jinzhou was 341.70/100 000 during 2010-2013 (382.71/100 000 in males and 302.02/100 000 in females). The standardized mortality rate was 318.55/100 000, the constituents in whole death causes was 50.97%, the YPLL was 13 222.50 person-years, the YPLLR was 13.52 and the AYLL was 3.51 years perperson. The mortality rate was higher in males than in females(Z=3.09, P0.05). The mortality rate increased significantly in age group 65 years. Cardiac disease ranked first in death causes of cardio and cerebral vascular diseases, and cerebrovascular disease ranked first in the PYLL due to cardio and cerebral vascular diseases, the mortality rate of cerebrovascular diseases decreased yearly from 2010 to 2013. Conclusion The mortality rate of cardio and cerebral vascular diseases, which pose severe threat to people's the life and health, was at a high level in Jinzhou. It is necessary to strengthen the prevention and control of cardio-cerebral vascular diseases in middle aged and old people and conduct intervention in population at high risk. Both the population based strategy and high risk group targeted strategy should be taken in the future to reduce the risk factors for cardio-cerebral vascular diseases.