姜璎慈, 卫鹭, 夏仪, 袁祖英, 李颖. 2011-2015年上海市长宁区手足口病聚集性疫情流行病学和病原学特征分析[J]. 疾病监测, 2017, 32(7): 568-572. DOI: 10.3784/j.issn.1003-9961.2017.07.010
引用本文: 姜璎慈, 卫鹭, 夏仪, 袁祖英, 李颖. 2011-2015年上海市长宁区手足口病聚集性疫情流行病学和病原学特征分析[J]. 疾病监测, 2017, 32(7): 568-572. DOI: 10.3784/j.issn.1003-9961.2017.07.010
JIANG Ying-ci, WEI Lu, XIA Yi, YUAN Zu-ying, LI Ying. Epidemiology and etiology of hand, foot and mouth disease outbreaks in Changning,2011-2015[J]. Disease Surveillance, 2017, 32(7): 568-572. DOI: 10.3784/j.issn.1003-9961.2017.07.010
Citation: JIANG Ying-ci, WEI Lu, XIA Yi, YUAN Zu-ying, LI Ying. Epidemiology and etiology of hand, foot and mouth disease outbreaks in Changning,2011-2015[J]. Disease Surveillance, 2017, 32(7): 568-572. DOI: 10.3784/j.issn.1003-9961.2017.07.010

2011-2015年上海市长宁区手足口病聚集性疫情流行病学和病原学特征分析

Epidemiology and etiology of hand, foot and mouth disease outbreaks in Changning,2011-2015

  • 摘要: 目的 了解上海市长宁区2011-2015年手足口病聚集性疫情的流行特征,为开展更加科学有效的防控措施提供依据。方法 收集长宁区2011-2015年手足口病聚集性疫情数据信息,采用描述性流行病学方法进行分析。结果 2011-2015年长宁区共报告手足口病聚集性疫情227起,涉及病例839例,占总报告病例的24.47%(839/3 429)。聚集性疫情高峰集中在3-6月(51.10%,116/227),主要发生在托幼机构70.93%(161/227)。疫情发生后1 d内报告的占16.30%(37/227);疫情持续时间1~18 d,中位数为4 d,四分位数间距为2~6 d。疫情持续时间与措施反应时间呈正相关(r=0.318,P=0.001)。EV71引起的暴发高峰集中在5-6月,早于Cox A16和其他肠道病毒的流行高峰(6-7月)。聚集性疫情病原以EV71为主,占40.94%(70/171);每个季度病原检出种类不同,差异有统计学意义(2 =13.799,P=0.032)。结论 及时开展手足口病聚集性疫情调查处置可有效减少疫情持续时间,长宁区手足口病不同流行期病原检出种类不同。建议5-6月应积极开展监测,重点关注EV71引起的聚集性疫情,警惕重症病例发生。

     

    Abstract: Objective To understand the epidemiological and etiological characteristics of hand, foot and mouth disease (HFMD) outbreaks in Changning district, Shanghai, and provide scientific evidence for HFMD prevention and control. Methods The incidence data of HFMD epidemic from 2011 to 2015 in Changning were collected for a descriptive epidemiological analysis to understand the distribution and etiological characteristics of the epidemics. Results From January 2011 to December 2015, a total of 227 HFMD outbreaks were reported in Changning, involving 839 cases, accounting for 24.47% of total reported HFMD disease cases (839/3 429). The annual incidence peak of HFMD occurred during March-June (51.10%, 116/227). Up to 70.93% (161/227) of outbreaks occurred in child care settings. Totally 37 outbreaks (16.30%) were reported within 1 day. And the durations of outbreaks ranged from 1 to 18 days (median: 4 days), the inter-quartilerange was 2-6 days. The duration of the outbreak was positively correlated with the time to take response measures (r=0.318, P=0.001). The incidence peak caused by EV71 occurred during May-June, earlier than the peak of Cox A16 and other enteroviruses (during June-July). EV71 was the major pathogen, accounting for 40.94% (70/171); the pathogens detected differed in different quarters. The difference was significant (2 =13.799,P=0.032). Conclusion Early response to HFMD outbreak could effectively reduce the epidemic duration. The reporting management should be strengthened. HFMD pathogen differed in different season in Changning, and more attention should be paid to the clustering of HFMD cases caused by EV71 during May-June, especially the severe cases caused by EV71. The surveillance for HFMD pathogens, timely reporting and response should be strengthened to prevent and control the epidemics of HFMD.

     

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