李军宏, 李艺星, 邵祝军, 周海建, 宁桂军, 尹遵栋, 罗会明, 梁晓峰. 2009年中国流行性脑脊髓膜炎监测结果分析[J]. 疾病监测, 2010, 25(10): 770-774.
引用本文: 李军宏, 李艺星, 邵祝军, 周海建, 宁桂军, 尹遵栋, 罗会明, 梁晓峰. 2009年中国流行性脑脊髓膜炎监测结果分析[J]. 疾病监测, 2010, 25(10): 770-774.
LI Jun-hong, LI Yi-xing, SHAO Zhu-jun, ZHOU Hai-jian, NING Gui-jun, YIN Zun-dong, LUO Hui-ming, LIANG Xiao-feng. Surveillance of meningococcal disease in China,2009[J]. Disease Surveillance, 2010, 25(10): 770-774.
Citation: LI Jun-hong, LI Yi-xing, SHAO Zhu-jun, ZHOU Hai-jian, NING Gui-jun, YIN Zun-dong, LUO Hui-ming, LIANG Xiao-feng. Surveillance of meningococcal disease in China,2009[J]. Disease Surveillance, 2010, 25(10): 770-774.

2009年中国流行性脑脊髓膜炎监测结果分析

Surveillance of meningococcal disease in China,2009

  • 摘要: 目的 分析中国2009年流行性脑脊髓膜炎(流脑)发病情况及国家级监测点所在省流行病学监测和实验室监测结果,评价流脑流行现状及特征,为加强预防控制流脑暴发流行提供参考资料。 方法 利用国家级监测点所在省上报资料、法定传染病报告系统资料、流脑单病/专病监测信息报告管理系统资料、中国疾病预防控制中心(CDC)传染病预防控制所国家流脑实验室检测资料对2009年流脑监测结果进行分析。 结果 2009年全国流脑报告发病率0.05/10万, 国家级监测点中以安徽省发病数较多(76例);15岁儿童平均发病率为 0.23/10万,儿童、学生报告病例数分别占监测省报告病例总数的42.14%和30.07%。监测省报告病例中检出A群脑膜炎奈瑟菌(Neisseria meningitidis,Nm)占23.16%,B群占4.21%, C群Nm占65.26%;健康人群中检出A群Nm占10.87%,B群Nm占28.26%,C群Nm占22.83%;健康人群A群Nm抗体阳性率平均为75.51%,C群为65.71%。 结论 中国流脑C群Nm检出比例逐年增多,病例最多的安徽省已成为C群流脑病例为主;健康人群带菌以B群Nm为主,C群Nm抗体阳性率明显低于A群。应针对薄弱环节,继续加强流脑监测,防止流脑暴发、流行。

     

    Abstract: Objective To understand the incidence trend and characteristics of meningococcal disease in China and provide reference for the prevention and control of meningococcal disease. Methods The surveillance results in China in 2009 were evaluated by using meningococcal disease epidemic data reported by the provinces conducting the surveillance, through notifiable communicable diseases reporting system, through the specific reporting system of meningococcal disease and by the state laboratory of meningococcal disease in China CDC. Results The overall reported incidence of meningococcal disease in China was0.05/lakh, and the case number (76) was highest in Anhui province. The average incidence was 0.23/lakh children under 15 years old. The cases among children and students accounted for 42.14% and 30.07%, respectively. Among the strains of Neisseria meningitidis (Nm) isolated from the cases, serogroup A, B and C accounted for 23.16%,4.21% and 65.26% respectively; and among the strains of Nm isolated from healthy people, sreogroup A, B and C accounted for 10.87%,28.26% and 22.83% respectively. The antibody positive rate was 75.51% for serogroup A and 65.71% for sergroup C among healthy population. Conclusion The proportion of Nm serogroup C detected in China increased by years, and Nm serogroup C had been predominant in Anhui province. Nm serogroup B was the main strain detected in healthy carriers, and the antibody positive rate of Nm serogroup C was lower than Nm serogroup A. It is necessary to improve the surveillance to prevent the epidemic or outbreak of meningococcal disease.

     

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