Abstract: Objective To understand the etiological and epidemiological characteristic of 1 case of human infection of Streptococcus suis and provide evidences for the control and prevention of the disease. Methods Field Epidemiological survey was conducted for the patient and close contacts, The clinical data of the patients were analyzed and laboratory detection of related specimens was performed. Results The patient was diagnosed as infection of Streptococcus suis type 2 following the epidemiological survey, clinical diagnosis and laboratory tests. Conclusion To control the epidemic in pigs, to deal with the sick/dead pigs correctly and to have good personal hygienic protection among the slaughterhouse workers are the effective measures to control and prevent the human infection of Streptococcus suis