徐翠玲, 孙闪华, 张彦平, 史景红, 向妮娟, 汪立杰, 袁帆, 陈敏, 陈涛, 杨静, 杨丽梅, 杨道威, 徐鹏, 张洋, 李培龙, 赵勇, 樊春祥, 赵庆龙, 宗俊, 王世文, 舒跃龙. 2009-2010年中国内地甲型H1N1流感确诊病例流行特征分析[J]. 疾病监测, 2011, 26(10): 780-784.
引用本文: 徐翠玲, 孙闪华, 张彦平, 史景红, 向妮娟, 汪立杰, 袁帆, 陈敏, 陈涛, 杨静, 杨丽梅, 杨道威, 徐鹏, 张洋, 李培龙, 赵勇, 樊春祥, 赵庆龙, 宗俊, 王世文, 舒跃龙. 2009-2010年中国内地甲型H1N1流感确诊病例流行特征分析[J]. 疾病监测, 2011, 26(10): 780-784.
XU Cui-ling, SUN Shan-hua, ZHANG Yan-ping, SHI Jing-hong, XIANG Ni-juan, WANG Li-jie, YUAN Fan, CHEN Min, CHEN Tao, YANG Jing, YANG Li-mei, YANG Dao-wei, XU Peng, ZHANG Yang, LI Pei-long, ZHAO Yong, FAN Chun-xiang, ZHAO Qing-long, ZONG Jun, WANG Shi-wen, SHU Yue-long. Epidemiological characteristics of confirmed cases of pandemic influenza A (H1N1) 2009 in mainland China, 2009-2010[J]. Disease Surveillance, 2011, 26(10): 780-784.
Citation: XU Cui-ling, SUN Shan-hua, ZHANG Yan-ping, SHI Jing-hong, XIANG Ni-juan, WANG Li-jie, YUAN Fan, CHEN Min, CHEN Tao, YANG Jing, YANG Li-mei, YANG Dao-wei, XU Peng, ZHANG Yang, LI Pei-long, ZHAO Yong, FAN Chun-xiang, ZHAO Qing-long, ZONG Jun, WANG Shi-wen, SHU Yue-long. Epidemiological characteristics of confirmed cases of pandemic influenza A (H1N1) 2009 in mainland China, 2009-2010[J]. Disease Surveillance, 2011, 26(10): 780-784.

2009-2010年中国内地甲型H1N1流感确诊病例流行特征分析

Epidemiological characteristics of confirmed cases of pandemic influenza A (H1N1) 2009 in mainland China, 2009-2010

  • 摘要: 目的 分析中国内地甲型H1N1流感(甲流)确诊病例的流行病学特点,为更好地防控流感疫情提供借鉴。 方法 对上报疾病监测信息报告管理系统的甲流确诊、住院、死亡病例进行描述性流行病学分析,对甲流平均检测阳性率进行时间分布分析。 结果 截至2010年7月4日,我国内地累计报告确诊病例127 885例,其中住院(含死亡)31 651例,死亡805例。2009年5月10日,报告首例输入性甲流确诊病例,截至7月18日每周新增报告的境外输入性病例超过本地感染病例。截至8月30日每周报告病例数、报告病例的新增县(区)数、甲流检测阳性率均呈缓慢上升趋势,8月31日以后均迅速增加。Spearman相关性分析显示,确诊病例数与甲流检测阳性率趋势一致(P0.0001)。11月23-29日所在周报告的确诊、住院、死亡病例数均达到峰值。截至2010年1月底,累计确诊病例中6~15岁所占比例(43.5%)和发病率(2750/10万)均最高;学生占66.3%。各年龄组中,25岁年龄组住院率最高;5岁人群死亡率最高,其次为15~24岁。 结论 2009-2010年我国内地出现一个甲流流行高峰,流行分为4个阶段:传入期、低流行期、流行高峰期、流行后期。学龄儿童、青少年和年轻成年人甲型H1N1感染发病的风险最高,儿童、青少年和年轻成年人发生严重病情的风险也最高。

     

    Abstract: Objective To understand the epidemiological characteristics of the confirmed cases of pandemic influenza A (H1N1) 2009 (2009 H1N1) in mainland China and provide evidence for the better prevention and control of influenza. Methods Descriptive epidemiological analysis was conducted on the incidence data of confirmed, hospitalized and fatal cases of 2009 H1N1reported through national disease reporting information system, and the time distribution of positive detection rate of 2009 H1N1 virus. Results As of July 4, 2010, a total of 1 275 885 of confirmed cases of 2009 H1N1 had been reported, including 31 651 hospitalized cases (including fatal cases) and 805 fatal cases. The first imported confirmed case was reported on May 10, 2009. The majority of confirmed cases reported weekly were imported from other countries before July 19. The case number, affected county (district) number and positive detection rate reported weekly increased slowly before 30 August and increased rapidly after 31 August. Spearman correlation analysis indicated that the confirmed case number was consistent with the trend of positive detection rate (P0.0001). The reported numbers of confirmed cases, hospitalized cases and fatal cases peaked during 23-29 November. At the end of January 2010, the proportion of confirmed cases and incidence were highest in age group of 6-15 years (43.5%, 275/1 million), among the cases in this age group, students accounted for 66.3%. The hospitalization rate was highest in age group of 25 years, and the death rate was highest in age group of 5 years, followed by age group of 15-24 years. Conclusion The transmission of pandemic influenza A (H1N1) in mainland China during 2009-2010 could be divided into 4 periods: importation period, low incidence period, peak period and post transmission period. School aged children, adolescents and young adults had the highest risk to be infected with 2009 H1N1 virus or develop severe symptoms..

     

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