何海艳, 赵莹, 吴伟慎, 李超, 单爱兰. 2010年天津市健康人群乙型病毒性肝炎病毒血清流行病学分析[J]. 疾病监测, 2011, 26(12): 939-942.
引用本文: 何海艳, 赵莹, 吴伟慎, 李超, 单爱兰. 2010年天津市健康人群乙型病毒性肝炎病毒血清流行病学分析[J]. 疾病监测, 2011, 26(12): 939-942.
HE Hai-yan, ZHAO Ying, WU Wei-shen, LI Chao, SHAN Ai-lan. Seroepidemiology of hepatitis B in healthy population in Tianjin, 2010[J]. Disease Surveillance, 2011, 26(12): 939-942.
Citation: HE Hai-yan, ZHAO Ying, WU Wei-shen, LI Chao, SHAN Ai-lan. Seroepidemiology of hepatitis B in healthy population in Tianjin, 2010[J]. Disease Surveillance, 2011, 26(12): 939-942.

2010年天津市健康人群乙型病毒性肝炎病毒血清流行病学分析

Seroepidemiology of hepatitis B in healthy population in Tianjin, 2010

  • 摘要: 目的 了解2010年天津市不同年龄段的健康人群乙型病毒性肝炎(乙肝)病毒(HBV)感染或免疫状况。 方法 根据年龄段和职业,在全市16个区(县)中采取分层整群随机抽样方法确定目标人群,对目标人群采用统一的调查表,调查登记与HBV感染和乙肝疫苗免疫相关的信息。 结果 1~59岁健康人群HBV表面抗原(HBsAg)、表面抗体(抗-HBs) 和核心抗体阳性率分别为2.63%、47.63%和10.15%;HBsAg阳性率:男性3.52%、女性1.73%,差异有统计学意义(2=13.78,P0.05),且随年龄的增长而逐渐升高,差异有统计学意义(2=30.39,P0.05);滨海三区最高(4.17%),市内六区最低(1.85%),地区间差异有统计学意义(2=9.59,P0.05);农民最高(4.44%),10岁儿童最低(0.38%)。抗-HBs阳性率:男性与女性基本一致,且随年龄的增长而显著降低,差异有统计学意义(2=302.06,P0.05)。 结论 新抽样方法适于现时期入户采血难的形势,且研究结果同样具有代表性。

     

    Abstract: Objective To understand the current status of hepatitis B virus (HBV) infection among the healthy population in Tianjin. Methods The survey of HBV infection status and hepatitis B vaccination was conducted among the healthy population selected in 16 counties (district) in Tianjin with stratified cluster random sampling. Results The results showed that the positive rates of HBsAg, anti-HBs and anti-HBc were 2.63%, 47.63% and 10.15% respectively. The positive rate of HBsAg was significantly higher in males (3.52%) than in females (1.73%) and increased with age (2=30.39, P0.05); The positive rate of HBsAg varied with areas, which was highest in coastal area (4.17%) and lowest in urban area (1.85%), the difference was statistical significant (2=9.59, P0.05). The positive rate of HBsAg was highest in farmers (4.44%) and lowest in children aged 10 years (0.38%). The positive rates of anti-HBs were similar between males and females, which declined with age. Conclusion The new sampling method was suitable for the serological surveillance of hepatitis B in the context of the difficulty existing in household survey for collecting blood sample and the result of the study was representative.

     

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