Abstract: specimens of RFIs cases were assayed for measles IgM antibody in 1999. The seropositive rate of measles antibodies was 59.30%; those of measles antibodies negative were then detected for rubella IgM antibodies, and the positive rate was 45.80%. The results showed that measles positive cases gathered in the age group of 4-14 years (89.2%). 77.33% of the positive cases had no vaccination history or no detail records. 20.90% cases were floating population, in which 17 cases had measles IgM positive antibodies,and only a few of them had vaccination histories.Form above results,we should consider that the basic immunization and revaccination should be strengthened,so did the flating population.In addition,while controlling measles outbreak and sporadic cases,we should strengthen the rubella surveillance.